Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2436007 | 0.89 | NR1H4 (0.52) | NR1H4KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL2436006 | 0.89 | NR1H4 (0.52) | NR1H4KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL2301703 | 0.88 | LTB4R (0.48) | NR1H4KMT2AMEN1LTB4RLTB4R2 | |
| SCHEMBL13221558 | 0.87 | NR1H4 (0.52) | NR1H4KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL2434019 | 0.87 | NR1H4 (0.52) | NR1H4KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL2434020 | 0.87 | NR1H4 (0.52) | NR1H4KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL2301698 | 0.83 | NR1H4 (0.47) | NR1H4KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL2301696 | 0.83 | NR1H4 (0.47) | NR1H4KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL5607559 | 0.81 | NR1H4 (0.77) | NR1H4KMT2AMEN1ALDH1A1EPHX2 | |
| SCHEMBL15668975 | 0.79 | LMNA (0.53) | NR1H4LMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367793-A1 | GPR120 RECEPTOR AGONISTS AND USES THEREOF | Metabolex Inc. (US) | 2011-09-28 | — | — | EP | disclosed |
| WO-2010080537-A1 | GPR120 RECEPTOR AGONISTS AND USES THEREOF | METABOLEX, INC. (US) | 2010-07-15 | — | — | WO | disclosed |