SCHEMBL24361998

SCHEMBL24361998

Bc1cc(Cl)cc2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 6/20 0.44
ALDH1A1 P00352 3/20 0.41
HSD17B10 Q99714 3/20 0.41
HIF1A Q16665 1/20 0.41
CYP1B1 Q16678 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
CYP1A2 P05177 4/20 0.39
TRPM4 Q8TD43 1/20 0.37
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
HTR2A P28223 1/20 0.35
NQO2 P16083 1/20 0.35
FADS1 O60427 1/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
GPR84 Q9NQS5 1/20 0.35
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
GLA P06280 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5024019 0.76 CYP2A6 (0.54) CYP2A6ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL30366335 0.76 CYP2A6 (0.54) CYP2A6ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL13191613 0.73 ALDH1A1 (0.52) CYP2A6ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL6416996 0.73 CYP1A2 (0.61) CYP2A6ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL21554160 0.73 HPRT1 (0.47) CYP2A6ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL19016678 0.73 CYP2A6 (0.44) CYP2A6ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL4960110 0.73 NQO2 (0.61) CYP2A6ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL15351928 0.73 CYP2A6 (0.44) CYP2A6ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL4767088 0.73 CYP2A6 (0.44) CYP2A6ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL9500074 0.73 CYP2A6 (0.44) CYP2A6ALDH1A1HSD17B10HIF1ACYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022086171-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2022-04-28 WO disclosed