Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.39 |
| ▸ | GLRB | P48167 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11388194 | 0.74 | GLRA3 (0.41) | LMNAGLRA3GLRBL3MBTL1POLB | |
| SCHEMBL4730281 | 0.70 | GLRA3 (0.38) | LMNAGLRA3GLRBL3MBTL1POLB | |
| SCHEMBL4002783 | 0.66 | LMNA (0.55) | LMNAGLRA3GLRBL3MBTL1ALDH1A1 | |
| SCHEMBL6748799 | 0.66 | — | — | |
| SCHEMBL16014567 | 0.64 | ALOX15 (0.47) | L3MBTL1POLBTDP1ALDH1A1KDM4E | |
| SCHEMBL19580224 | 0.64 | GPR35 (0.46) | LMNAGLRA3GLRBL3MBTL1POLB | |
| SCHEMBL3470368 | 0.64 | GPR35 (0.42) | L3MBTL1POLBTDP1KDM4EDAO | |
| SCHEMBL13714042 | 0.63 | POLB (0.43) | L3MBTL1POLBTDP1ALDH1A1KDM4E | |
| SCHEMBL31588020 | 0.61 | GLRA3 (0.43) | GLRA3GLRBPOLBTDP1ALDH1A1 | |
| SCHEMBL13208593 | 0.61 | KDM4E (0.46) | LMNAGLRA3GLRBL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106627-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |