SCHEMBL2436662

SCHEMBL2436662

O=C1N[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
IDUA P35475 1/20 0.47
GLA P06280 3/20 0.44
GAA P10253 3/20 0.44
AGL P35573 2/20 0.44
GBA2 Q9HCG7 1/20 0.44
GBA1 P04062 1/20 0.44
MGAM O43451 5/20 0.42
FUCA1 P04066 4/20 0.42
GANC Q8TET4 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2269870 1.00 IDUA (0.47) IDUAGLAGAAAGLGBA2
SCHEMBL8878544 1.00 IDUA (0.47) IDUAGLAGAAAGLGBA2
SCHEMBL2270633 1.00 IDUA (0.47) IDUAGLAGAAAGLGBA2
SCHEMBL19575262 1.00 IDUA (0.47) IDUAGLAGAAAGLGBA2
SCHEMBL4606758 0.93 MAN2B1 (0.45) IDUAGLAGAAAGLGBA2
SCHEMBL4605168 0.93 MAN2B1 (0.45) IDUAGLAGAAAGLGBA2
SCHEMBL15031115 0.78 GLA (0.41) GLAGAAAGLGBA2GBA1
SCHEMBL13367189 0.78 GLA (0.41) GLAGAAAGLGBA2GBA1
SCHEMBL16134370 0.78 FUCA1 (0.43) GLAGAAAGLGBA2GBA1
SCHEMBL13339121 0.78 GLA (0.41) GLAGAAAGLGBA2GBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3679153-A1 GENERATION OF WATER-SOLUBLE CANNABINOID COMPOUNDS IN YEAST AND PLANT CELL SUSPENSION CULTURES AND COMPOSITIONS OF MATTER Trait Biosciences, Inc. (US) 2020-07-15 EP claimed
WO-2020081739-A1 SYSTEMS, METHODS, AND COMPOSITIONS FOR THE PRODUCTION OF WATER-SOLUBLE TERPENES DERIVED FROM CANNABIS PLANTS TRAIT BIOSCIENCES, INC. (US) 2020-04-23 WO claimed
US-20190078168-A1 Generation of Water-Soluble Cannabinoid Compounds in Yeast and Plant Cell Suspension Cultures and Compositions of Matter TRAIT BIOSCIENCES INC., TRAIT NM INC., TRAIT BIOSCIENCES (CANADA) INC., AND TWIGG PHARMA LTD. 2019-03-14 US claimed
WO-2019014395-A1 GENERATION OF WATER-SOLUBLE CANNABINOID COMPOUNDS IN YEAST AND PLANT CELL SUSPENSION CULTURES AND COMPOSITIONS OF MATTER TRAIT BIOSCIENCES, INC. (US) 2019-01-17 WO claimed
US-20240301449-A1 PRODUCTION OF CANNABINOID GLYCOSIDE COMPOUNDS IN CELL CULTURE TRAIT BIOSCIENCES INC (US) 2024-09-12 US disclosed
US-20240207179-A1 WATER-SOLUBLE CANNABINOID FOOD AND BEVERAGE ADDITIVE HAVING ENHANCED STABILITY TRAIT BIOSCIENCES INC (US) 2024-06-27 US disclosed
US-11946059-B2 In vivo generation of water-soluble cannabinoids in plant cell suspension cultures TRAIT BIOSCIENCES, INC. (US) 2024-04-02 US disclosed
US-11905543-B2 In vivo generation of water-soluble acetylated cannabinoid glycoside compounds in plant cell suspension cultures TRAIT BIOSCEINCES, INC. (US) 2024-02-20 US disclosed
US-11466281-B2 Generation of water-soluble cannabinoid compounds in yeast and plant cell suspension cultures and compositions of matter Trait Biosciences Inc. (US) 2022-10-11 US disclosed
US-20220267820-A1 Compositions And Methods For Glycosylating Cannabinoid Compounds TRAIT BIOSCIENCES INC (US) 2022-08-25 US disclosed
US-20210348204-A1 Systems, Methods, And Compositions For The Production of Water-Soluble Terpenes Derived From Cannabis Plants TRAIT BIOSCIENCES, INC. 2021-11-11 US disclosed
EP-3730145-A1 GENERATION OF WATER-SOLUBLE CANNABINOID COMPOUNDS IN YEAST AND PLANT CELL SUSPENSION CULTURES AND COMPOSITIONS OF MATTER Trait Biosciences, Inc. (US) 2020-10-28 EP disclosed
US-20200046639-A1 CONSUMABLE WATER-SOLUBLE CANNABINOID FOOD AND BEVERAGE ADDITIVE HAVING ENHANCED STABILITY TRAIT BIOSCIENCES INC., TRAIT NM INC., TRAIT BIOSCIENCES (CANADA) INC., AND TWIGG PHARMA LTD. 2020-02-13 US disclosed
US-20190316144-A1 IN VIVO GENERATION OF WATER-SOLUBLE CANNABINOIDS IN PLANT CELL SUSPENSION CULTURES TRAIT BIOSCIENCES INC., TRAIT NM INC., TRAIT BIOSCIENCES (CANADA) INC., AND TWIGG PHARMA LTD. 2019-10-17 US disclosed
US-20190194133-A1 GLYCOLACTAM COMPOUNDS, PROCESS FOR PREPARATION AND USES THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2019-06-27 US disclosed
US-20190078168-A1 Generation of Water-Soluble Cannabinoid Compounds in Yeast and Plant Cell Suspension Cultures and Compositions of Matter TRAIT BIOSCIENCES INC., TRAIT NM INC., TRAIT BIOSCIENCES (CANADA) INC., AND TWIGG PHARMA LTD. 2019-03-14 US disclosed
WO-2019014395-A1 GENERATION OF WATER-SOLUBLE CANNABINOID COMPOUNDS IN YEAST AND PLANT CELL SUSPENSION CULTURES AND COMPOSITIONS OF MATTER TRAIT BIOSCIENCES, INC. (US) 2019-01-17 WO disclosed
WO-2017191657-A1 GLYCOLACTAM COMPOUNDS, PROCESS FOR PREPARATION AND USES THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2017-11-09 WO disclosed
US-20110237538-A1 TREATMENT OF LYSOSOMAL STORAGE DISORDERS AND OTHER PROTEOSTATIC DISEASES SUMMIT CORPORATION PLC (GB) 2011-09-29 US disclosed
EP-2351484-A1 PARASITIC PLANT CONTROL AGENT AND PARASITIC PLANT CONTROL METHOD Osaka University (JP) 2011-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110237538-A1 TREATMENT OF LYSOSOMAL STORAGE DISORDERS AND OTHER PROTEOSTATIC DISEASES GAA, MAN2B1, GBA1 IDUA 9/4885GLA 13/4885GAA 1/4885
US-20210348204-A1 Systems, Methods, And Compositions For The Production of Water-Soluble Terpenes Derived From Cannabis Plants UGCG, TRRAP, ENGASE IDUA 681/4885GLA 192/4885GAA 1317/4885
US-11905543-B2 In vivo generation of water-soluble acetylated cannabinoid glycoside compounds in plant cell suspension cultures CNR2, CNR1, FAAH IDUA 1755/4885GLA 227/4885GAA 972/4885
US-20200046639-A1 CONSUMABLE WATER-SOLUBLE CANNABINOID FOOD AND BEVERAGE ADDITIVE HAVING ENHANCED STABILITY CNR1, CNR2, FAAH IDUA 2629/4885GLA 3916/4885GAA 1927/4885
US-20190194133-A1 GLYCOLACTAM COMPOUNDS, PROCESS FOR PREPARATION AND USES THEREOF GALNT14, GALNT10, GALNT3 IDUA 904/4885GLA 94/4885GAA 789/4885
US-11946059-B2 In vivo generation of water-soluble cannabinoids in plant cell suspension cultures CNR2, CNR1, FAAH IDUA 2600/4885GLA 2321/4885GAA 3658/4885
US-20240301449-A1 PRODUCTION OF CANNABINOID GLYCOSIDE COMPOUNDS IN CELL CULTURE CNR2, CNR1, UGCG IDUA 2557/4885GLA 852/4885GAA 1570/4885
US-20190316144-A1 IN VIVO GENERATION OF WATER-SOLUBLE CANNABINOIDS IN PLANT CELL SUSPENSION CULTURES CNR2, CNR1, FAAH IDUA 2600/4885GLA 2321/4885GAA 3658/4885
US-20240207179-A1 WATER-SOLUBLE CANNABINOID FOOD AND BEVERAGE ADDITIVE HAVING ENHANCED STABILITY CNR2, CNR1, GPR18 IDUA 2703/4885GLA 3410/4885GAA 1845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.