Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAN2B1 | O00754 | 1/20 | 0.45 |
| ▸ | IDUA | P35475 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | AGL | P35573 | 2/20 | 0.40 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 5/20 | 0.39 |
| ▸ | FUCA1 | P04066 | 4/20 | 0.39 |
| ▸ | GANC | Q8TET4 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4605168 | 1.00 | MAN2B1 (0.45) | MAN2B1IDUAGLAGAAAGL | |
| SCHEMBL8878544 | 0.93 | IDUA (0.47) | IDUAGLAGAAAGLGBA2 | |
| SCHEMBL2436662 | 0.93 | IDUA (0.47) | IDUAGLAGAAAGLGBA2 | |
| SCHEMBL2269870 | 0.93 | IDUA (0.47) | IDUAGLAGAAAGLGBA2 | |
| SCHEMBL2270633 | 0.93 | IDUA (0.47) | IDUAGLAGAAAGLGBA2 | |
| SCHEMBL19575262 | 0.93 | IDUA (0.47) | IDUAGLAGAAAGLGBA2 | |
| SCHEMBL12232896 | 0.77 | GLA (0.37) | MAN2B1IDUAGLAGAAAGL | |
| SCHEMBL15031115 | 0.76 | GLA (0.41) | GLAGAAAGLGBA2GBA1 | |
| SCHEMBL13367189 | 0.76 | GLA (0.41) | GLAGAAAGLGBA2GBA1 | |
| SCHEMBL16134370 | 0.76 | FUCA1 (0.43) | GLAGAAAGLGBA2GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1947084-A2 | 2-Pyrrolidones as intermediates for the preparation of pyrrolidines | MICHIGAN STATE UNIVERSITY (US) | 2008-07-23 | — | — | EP | claimed |
| EP-1305284-A4 | PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES | UNIV MICHIGAN STATE (US) | 2005-08-03 | — | — | EP | claimed |
| EP-1305284-A1 | PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES | MICHIGAN STATE UNIVERSITY (US) | 2003-05-02 | — | — | EP | claimed |
| US-20020026071-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES, OPERATING MICHIGAN STATE UNIVERSITY | 2002-02-28 | — | — | US | claimed |
| US-20020026073-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2002-02-28 | — | — | US | claimed |
| US-20020026072-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 2002-02-28 | — | — | US | claimed |
| US-20020026074-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERS | 2002-02-28 | — | — | US | claimed |
| US-20020019542-A1 | Process and intermediate compounds for the preparation of pyrrolidines | MICHIGAN STATE UNIVERSITY BOARD OF TRUSTEES OPERATING | 2002-02-14 | — | — | US | claimed |
| US-20020019561-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2002-02-14 | — | — | US | claimed |
| WO-2002010130-A1 | PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES | MICHIGAN STATE UNIVERSITY (US) | 2002-02-07 | — | — | WO | claimed |
| EP-1947084-A2 | 2-Pyrrolidones as intermediates for the preparation of pyrrolidines | MICHIGAN STATE UNIVERSITY (US) | 2008-07-23 | — | — | EP | disclosed |
| EP-1947084-A2 | 2-Pyrrolidones as intermediates for the preparation of pyrrolidines | MICHIGAN STATE UNIVERSITY (US) | 2008-07-23 | — | — | EP | disclosed |
| EP-1947082-A2 | Oximes or imines of 4-pentulosonic acid methyl esters as intermediates for the preparation of pyrrolidines | MICHIGAN STATE UNIVERSITY (US) | 2008-07-23 | — | — | EP | disclosed |
| EP-1305284-A4 | PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES | UNIV MICHIGAN STATE (US) | 2005-08-03 | — | — | EP | disclosed |
| US-6583297-B2 | From tri-O-acetyl-D-erythro-4-pentulosonic acid esters | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2003-06-24 | — | — | US | disclosed |
| US-20020026071-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES, OPERATING MICHIGAN STATE UNIVERSITY | 2002-02-28 | — | — | US | disclosed |
| US-20020026073-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2002-02-28 | — | — | US | disclosed |
| US-20020019542-A1 | Process and intermediate compounds for the preparation of pyrrolidines | MICHIGAN STATE UNIVERSITY BOARD OF TRUSTEES OPERATING | 2002-02-14 | — | — | US | disclosed |
| US-20020019561-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2002-02-14 | — | — | US | disclosed |
| WO-2002010130-A1 | PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES | MICHIGAN STATE UNIVERSITY (US) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020026073-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | MAN2B1 798/4885IDUA 563/4885GLA 959/4885 |
| US-20020026071-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | MAN2B1 798/4885IDUA 563/4885GLA 959/4885 |
| US-20020019542-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | MAN2B1 798/4885IDUA 563/4885GLA 959/4885 |
| US-20020026074-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | MAN2B1 798/4885IDUA 563/4885GLA 959/4885 |
| US-20020026072-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | MAN2B1 798/4885IDUA 563/4885GLA 959/4885 |
| US-20020019561-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | MAN2B1 798/4885IDUA 563/4885GLA 959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.