Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11677753 | 0.89 | ALDH1A1 (0.50) | ALDH1A1CYP3A4PDE7AHTTPOLB | |
| SCHEMBL4914101 | 0.86 | ALDH1A1 (0.58) | ALDH1A1CYP3A4PDE7AHTTPOLB | |
| SCHEMBL28588307 | 0.84 | ALDH1A1 (0.46) | ALDH1A1CYP3A4PDE7AHTTPOLB | |
| SCHEMBL11649757 | 0.84 | ALDH1A1 (0.50) | ALDH1A1CYP3A4PDE7AHTTPOLB | |
| SCHEMBL219209 | 0.82 | ALDH1A1 (0.80) | ALDH1A1CYP3A4HTTPOLBSMN1; SMN2 | |
| SCHEMBL31618848 | 0.82 | ALDH1A1 (0.44) | ALDH1A1CYP3A4PDE7AHTTPOLB | |
| SCHEMBL29250782 | 0.82 | ALDH1A1 (0.44) | ALDH1A1CYP3A4PDE7AHTTPOLB | |
| SCHEMBL15271018 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CYP3A4PDE7AHTTPOLB | |
| SCHEMBL9186844 | 0.81 | ALDH1A1 (0.46) | ALDH1A1CYP3A4PDE7AHTTPOLB | |
| SCHEMBL29945744 | 0.81 | ALDH1A1 (0.45) | ALDH1A1CYP3A4PDE7AHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023118267-A1 | NOVEL GALACTOSIDE INHIBITOR OF GALECTINS | GALECTO BIOTECH AB (DK) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023118267-A1 | NOVEL GALACTOSIDE INHIBITOR OF GALECTINS | GALECTO BIOTECH AB (DK) | 2023-06-29 | — | — | WO | disclosed |
| US-9938411-B2 | Disperse azo dyes | HUNTSMAN INTERNATIONAL LLC (US) | 2018-04-10 | — | — | US | disclosed |
| EP-2655518-B1 | DISPERSE AZO DYES | HUNTSMAN ADV MAT SWITZERLAND (CH) | 2016-01-06 | — | — | EP | disclosed |
| EP-2655518-A1 | DISPERSE AZO DYES | Huntsman Advanced Materials (Switzerland) GmbH (CH) | 2013-10-30 | — | — | EP | disclosed |
| US-20130255011-A1 | Disperse Azo Dyes | HUNTSMAN INTERNATIONAL LLC (US) | 2013-10-03 | — | — | US | disclosed |
| US-8299075-B2 | Substituted thiomorpholine derivatives | H. LUNDBECK A/S (DK) | 2012-10-30 | — | — | US | disclosed |
| WO-2012084417-A1 | DISPERSE AZO DYES | HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) | 2012-06-28 | — | — | WO | disclosed |
| CN-102516204-A | Substituted morpholine and thiomorpholine derivatives | LUNDBECK & CO AS H | 2012-06-27 | — | — | CN | disclosed |
| US-20110294787-A1 | SUBSTITUTED THIOMORPHOLINE DERIVATIVES | H. LUNDBECK A/S (DK) | 2011-12-01 | — | — | US | disclosed |
| EP-0039312-A1 | Colour photopgraphic material for the silver-dye bleaching process, process for the production of this material and its use in the production of photographic images | CIBA-GEIGY AG (CH) | 1981-11-04 | — | — | EP | disclosed |
| US-4293566-A | FUNGICIDES, BACTERICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-06 | — | — | US | disclosed |
| US-4250089-A | Process for diazotizing aromatic amines | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-10 | — | — | US | disclosed |
| US-4237048-A | COLORFASTNESS; FOR DYEING NATURAL AND SYNTHETIC FIBERS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-02 | — | — | US | disclosed |
| US-4183949-A | Pesticidally active 1-arylamino-2,4-dinitronaphthalenes | BAYER AKTIENGESELLSCHAFT (DE) | 1980-01-15 | — | — | US | disclosed |
| US-4105655-A | PHENYL-AZO-ANILINO DYESTUFF | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-08 | — | — | US | disclosed |
| US-4083844-A | Phenylazo orthocyano phenylazo or orthocyano phenylazo phenylazo containing dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1978-04-11 | — | — | US | disclosed |
| US-3978040-A | Process for the preparation of cyanoazo compounds by reacting halogenoazo compounds with CuCN in an aqueous media in the presence of a nitrogen base | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-31 | — | — | US | disclosed |
| US-3976633-A | ANORECTIC, ANTIOBESITY | SMITHKLINE CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |
| US-3962209-A | PROCESS FOR PREPARING AZO DYESTUFFS WITH ORTHO-AZO CYANO GROUPS BY CYANO EXCHANGE OF METAL CYANIDES AND HALO DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294787-A1 | SUBSTITUTED THIOMORPHOLINE DERIVATIVES | OPRM1, OPRK1, OPRL1 | ALDH1A1 1483/4885CYP3A4 82/4885PDE7A 1197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.