Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24369909 | 0.72 | CNR2 (0.48) | POLB | |
| SCHEMBL29570850 | 0.72 | CNR2 (0.48) | POLB | |
| SCHEMBL31106550 | 0.71 | METAP1 (0.42) | PGRCYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL28517437 | 0.71 | METAP1 (0.42) | PGRCYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL5648628 | 0.71 | PGR (0.49) | PGRCYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL30695369 | 0.68 | CYP3A4 (0.41) | CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL9770689 | 0.68 | CYP3A4 (0.41) | CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL31106547 | 0.65 | RXRA (0.44) | CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL5646023 | 0.65 | RXRA (0.44) | CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL1615553 | 0.64 | RXRA (0.46) | CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12595234-B2 | Bioactive benzocycloheptene analogues from himachalenes and its applications | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2026-04-07 | — | — | US | disclosed |
| US-20230382860-A1 | Bioactive Benzocycloheptene Analogues From Himachalenes and its Applications | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-11-30 | — | — | US | disclosed |
| US-20230382860-A1 | Bioactive Benzocycloheptene Analogues From Himachalenes and its Applications | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-11-30 | — | — | US | disclosed |
| US-20230382860-A1 | Bioactive Benzocycloheptene Analogues From Himachalenes and its Applications | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-11-30 | — | — | US | disclosed |
| EP-4232441-A1 | BIOACTIVE BENZOCYCLOHEPTENE ANALOGUES FROM HIMACHALENES AND ITS APPLICATIONS | Council of Scientific & Industrial Research (IN) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022085023-A1 | BIOACTIVE BENZOCYCLOHEPTENE ANALOGUES FROM HIMACHALENES AND ITS APPLICATIONS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-04-28 | — | — | WO | disclosed |
| WO-2022085023-A1 | BIOACTIVE BENZOCYCLOHEPTENE ANALOGUES FROM HIMACHALENES AND ITS APPLICATIONS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12595234-B2 | Bioactive benzocycloheptene analogues from himachalenes and its applications | CNR2, HK2, PIK3C2A | PGR 1117/4885CYP1A2 346/4885POLB 3335/4885 |
| US-20230382860-A1 | Bioactive Benzocycloheptene Analogues From Himachalenes and its Applications | HK2, GPR119, PIK3CD | PGR 1154/4885CYP1A2 79/4885POLB 3211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.