Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25156142 | 0.78 | ALDH1A1 (0.48) | ALDH1A1 | |
| SCHEMBL10068912 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TSHR | |
| SCHEMBL17195722 | 0.75 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL13826574 | 0.73 | ALDH1A1 (0.52) | ALDH1A1 | |
| SCHEMBL8680271 | 0.71 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL13188529 | 0.69 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL10289960 | 0.69 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL12283869 | 0.69 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL3780096 | 0.68 | ALDH1A1 (0.46) | ALDH1A1TSHR | |
| SCHEMBL285229 | 0.68 | ALDH1A1 (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022084741-A1 | CFTR MODULATOR COMPOUNDS, COMPOSITIONS, AND USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-04-28 | — | — | WO | disclosed |