SCHEMBL8680271

SCHEMBL8680271

C=C(C=C(Cl)Cl)C(=O)OC

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
KEAP1 Q14145 1/20 0.31
NFE2L2 Q16236 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13826574 0.78 ALDH1A1 (0.52) ALDH1A1KEAP1NFE2L2HCAR2
SCHEMBL25156142 0.74 ALDH1A1 (0.48) ALDH1A1
SCHEMBL13346981 0.74 ALDH1A1 (0.34) ALDH1A1
SCHEMBL3780096 0.73 ALDH1A1 (0.46) ALDH1A1
SCHEMBL285229 0.73 ALDH1A1 (0.46) ALDH1A1
SCHEMBL25948261 0.73 ALDH1A1 (0.46) ALDH1A1
SCHEMBL1557823 0.72
SCHEMBL27439378 0.72
SCHEMBL28127590 0.71
SCHEMBL20325317 0.71 ALDH1A1 (0.44) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5759734-A Method of generating simulated photographic-quality images on luminescent melt-formed backing substrates XEROX CORPORATION (US) 1998-06-02 US claimed
US-5759727-A TONER IMAGE ON TRANSPARENT SUBSTRATE; MELT POLYMER BACKING XEROX CORPORATION (US) 1998-06-02 US claimed