SCHEMBL24371230

SCHEMBL24371230

Cc1cn(C2CCC(CCO)O2)c(=O)[nH]c1=O

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TK1 P04183 6/20 0.56
LMNA P02545 3/20 0.56
TSHR P16473 2/20 0.56
ALB P02768 2/20 0.56
BLM P54132 2/20 0.56
PKM P14618 1/20 0.56
PMP22 Q01453 1/20 0.56
CYP2D6 P10635 1/20 0.56
ALDH1A1 P00352 1/20 0.52
POLB P06746 1/20 0.52
ADRA1A P35348 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27505365 0.89 LMNA (0.58) TK1LMNATSHRALBBLM
SCHEMBL14421795 0.89 LMNA (0.58) TK1LMNATSHRALBBLM
SCHEMBL925743 0.89 LMNA (0.58) TK1LMNATSHRALBBLM
SCHEMBL13286394 0.89 LMNA (0.58) TK1LMNATSHRALBBLM
SCHEMBL762579 0.89 LMNA (0.58) TK1LMNATSHRALBBLM
SCHEMBL29711774 0.89 LMNA (0.58) TK1LMNATSHRALBBLM
SCHEMBL23485 0.89 LMNA (0.58) TK1LMNATSHRALBBLM
SCHEMBL14596607 0.89 LMNA (0.58) TK1LMNATSHRALBBLM
SCHEMBL22992337 0.89 LMNA (0.58) TK1LMNATSHRALBBLM
SCHEMBL8920703 0.89 LMNA (0.58) TK1LMNATSHRALBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022083686-A1 MODIFIED NUCLEOSIDE OR NUCLEOTIDE 深圳华大生命科学研究院 2022-04-28 WO disclosed