Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 3/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1098298 | 0.76 | BCHE (0.39) | ALDH1A1METAP2LMNACAPN1BCHE | |
| SCHEMBL30590106 | 0.74 | BCHE (0.40) | ALDH1A1METAP2LMNACAPN1BCHE | |
| SCHEMBL23264568 | 0.74 | BCHE (0.38) | ALDH1A1METAP2LMNACAPN1BCHE | |
| SCHEMBL23264561 | 0.74 | BCHE (0.38) | ALDH1A1METAP2LMNACAPN1BCHE | |
| SCHEMBL19492341 | 0.73 | METAP2 (0.37) | ALDH1A1METAP2LMNACAPN1BCHE | |
| SCHEMBL704898 | 0.72 | CYP2C9 (0.34) | ALDH1A1METAP2CAPN1BCHEHTR2C | |
| SCHEMBL30590064 | 0.71 | LMNA (0.39) | ALDH1A1METAP2LMNACAPN1BCHE | |
| SCHEMBL19101763 | 0.71 | LMNA (0.39) | ALDH1A1METAP2LMNACAPN1BCHE | |
| SCHEMBL26121971 | 0.71 | LMNA (0.39) | ALDH1A1METAP2LMNACAPN1BCHE | |
| SCHEMBL21179976 | 0.70 | ALDH1A1 (0.35) | ALDH1A1METAP2LMNACAPN1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3043803-B1 | NUCLEOTIDE AND NUCLEOSIDE COMPOSITIONS AND THEIR USES | UNIV EMORY (US) | 2022-04-27 | — | — | EP | disclosed |