Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9362724 | 0.84 | MAOB (0.52) | MAOBMAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL14291457 | 0.84 | TSHR (0.49) | MAOBMAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL10481838 | 0.83 | MAPT (0.50) | MAOBMAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL5793118 | 0.82 | FFAR4 (0.47) | MAOBMAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL5795904 | 0.82 | L3MBTL1 (0.46) | MAOBMAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL7535983 | 0.81 | LMNA (0.53) | MAOBMAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL1143540 | 0.81 | MAOB (0.53) | MAOBMAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL348875 | 0.80 | MEN1 (0.55) | MAOBMAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL8555303 | 0.80 | KDM1A (0.49) | MAOBMAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL13403395 | 0.79 | LMNA (0.45) | MAOBMAPTL3MBTL1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3988561-A1 | PREPARATION AND USE OF REACTIVE OXYGEN SPECIES SCAVENGER | XWPharma Ltd. (KY) | 2022-04-27 | — | — | EP | disclosed |