Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 12/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24372381 | 0.99 | HSD11B1 (0.56) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL24372411 | 0.85 | HSD11B1 (0.54) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL31042808 | 0.84 | HSD11B1 (0.53) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL24372403 | 0.84 | HSD11B1 (0.53) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL24372378 | 0.82 | HSD11B1 (0.57) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL24372421 | 0.81 | HSD11B1 (0.56) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL5643459 | 0.73 | HSD11B1 (0.71) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL24372566 | 0.72 | ALDH1A1 (0.39) | KMT2AALDH1A1TSHRSMN1; SMN2DPP7 | |
| SCHEMBL348724 | 0.71 | HSD11B1 (1.00) | HSD11B1MEN1KMT2AALDH1A1 | |
| SCHEMBL3139523 | 0.71 | HSD11B1 (0.71) | HSD11B1MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3988090-A1 | P62 LIGAND COMPOUND AND ER-PHAGY-PROMOTING USE THEREOF | Protech Inc. (KR) | 2022-04-27 | — | — | EP | disclosed |