Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24372545 | 0.91 | ALDH1A1 (0.46) | ALDH1A1MAPK1L3MBTL1RAB9ANPC1 | |
| SCHEMBL24372550 | 0.89 | CYP1A2 (0.53) | ALDH1A1MAPK1L3MBTL1RAB9ANPC1 | |
| SCHEMBL498454 | 0.89 | ALDH1A1 (0.68) | ALDH1A1MAPK1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL11307628 | 0.87 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL21993645 | 0.86 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1RAB9ANPC1 | |
| SCHEMBL27789016 | 0.85 | MEN1 (0.58) | ALDH1A1MAPK1L3MBTL1RAB9ANPC1 | |
| SCHEMBL11137258 | 0.84 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1RAB9ANPC1 | |
| SCHEMBL6667842 | 0.82 | MAPT (0.55) | ALDH1A1MAPK1L3MBTL1RAB9ANPC1 | |
| SCHEMBL11545635 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1RAB9ANPC1 | |
| SCHEMBL11545647 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3935129-B1 | LIGANDS FOR NANO-SIZED MATERIALS | MERCK PATENT GMBH (DE) | 2023-11-29 | — | — | EP | disclosed |
| US-20220127286-A1 | LIGANDS FOR NANO-SIZED MATERIALS | MERCK PATENT GMBH (DE) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127286-A1 | LIGANDS FOR NANO-SIZED MATERIALS | L1CAM, EPCAM, SELPLG | ALDH1A1 3030/4885MAPK1 3818/4885L3MBTL1 3027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.