Sugi Predict

Sugi Predict / Compounds / SCHEMBL498454

SCHEMBL498454

SCHEMBL498454

O=C(CS)OCc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.68
▸ MAPK1 P28482 1/20 0.68
▸ L3MBTL1 Q9Y468 1/20 0.68
▸ TDP1 Q9NUW8 2/20 0.57
▸ SLC6A2 P23975 1/20 0.57
▸ SLC6A3 Q01959 1/20 0.57
▸ KMT2A Q03164 1/20 0.57
▸ LMNA P02545 3/20 0.52
▸ HCAR2 Q8TDS4 1/20 0.52
▸ CTRB1 P17538 2/20 0.50
▸ CYP1A2 P05177 1/20 0.50
▸ CYP2C9 P11712 1/20 0.50
▸ CYP2C19 P33261 1/20 0.50
▸ CDC25B P30305 1/20 0.50
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ CA12 O43570 1/20 0.47
▸ CA1 P00915 1/20 0.47
▸ CA2 P00918 1/20 0.47
▸ CA9 Q16790 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11307628 0.98 ALDH1A1 (0.66) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL11137258 0.94 ALDH1A1 (0.61) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL11545647 0.93 ALDH1A1 (0.59) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL11545635 0.93 ALDH1A1 (0.59) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
Toluene SCHEMBL11852942 0.91 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL11436137 0.89 ALDH1A1 (0.56) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL24372533 0.89 ALDH1A1 (0.55) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL24372729 0.84 ALDH1A1 (0.50) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL1200923 0.84 ALDH1A1 (0.63) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL28173072 0.83 MEN1 (0.57) ALDH1A1MAPK1L3MBTL1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119050267-B Positive electrode capable of limiting lattice oxygen escape and preparation method and application thereof 华中科技大学 2026-05-12 — — CN claimed
CN-119050267-A Positive electrode capable of limiting lattice oxygen escape and preparation method and application thereof 华中科技大学 2024-11-29 — — CN claimed
CN-112964705-B Reagent for detecting ethylenediamine by using dual modes of rapid colorimetric and fluorescent lighting 中国科学院新疆理化技术研究所 2022-06-03 — — CN claimed
CN-112964705-A Reagent for detecting ethylenediamine by using dual modes of rapid colorimetric and fluorescent lighting 中国科学院新疆理化技术研究所 2021-06-15 — — CN claimed
CN-108425104-B Preparation method of coating taking mercapto compound as transition layer 江苏菲沃泰纳米科技有限公司 2020-02-18 — — CN claimed
US-7732625-B2 Colorant compounds XEROX CORPORATION (US) 2010-06-08 — — US claimed
US-7311767-B2 Forming a salt of a liquid phase change ink carrier of stearyl stearamide, an amine substituted Xanthene, acridine, anthracene or thioxanthene chromogen, and a metal salt capable of forming a compound with two chromogens XEROX CORPORATION (US) 2007-12-25 — — US claimed
US-7033424-B2 Phase change inks XEROX CORPORATION (US) 2006-04-25 — — US claimed
US-20060021546-A1 Processes for preparing phase change inks XEROX CORPORATION 2006-02-02 — — US claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 — — US claimed
US-20060016369-A1 PHASE CHANGE INKS XEROX CORPORATION 2006-01-26 — — US claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 — — US claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 — — US claimed
CN-119050267-B Positive electrode capable of limiting lattice oxygen escape and preparation method and application thereof 华中科技大学 2026-05-12 — — CN disclosed
CN-116217553-B Triazinone compound and preparation method and application thereof 江西同和药业股份有限公司 2025-03-28 — — CN disclosed
US-12162888-B2 Carboxamides as ubiquitin-specific protease inhibitors VALO HEALTH, INC. (US) 2024-12-10 — — US disclosed
US-4120845-A FOR VINYL OR VINYLIDENE HALIDE POLYMERS CINCINNATI MILACRON CHEMICALS, INC. (US) 1978-10-17 — — US disclosed
US-RE29523-E Olefinic polymers stabilized with thioacyl trivalent phosphorus compounds BORG-WARNER CORPORATION (US) 1978-01-24 — — US disclosed
US-4062881-A POLYVINYL CHLORIDE CINCINNATI MILACRON CHEMICALS, INC. (US) 1977-12-13 — — US disclosed
US-4021407-A DISCOLORATION INHIBITION CINCINNATI MILACRON, INC. (US) 1977-05-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 ALDH1A1 1569/4885MAPK1 4104/4885L3MBTL1 598/4885
US-12162888-B2 Carboxamides as ubiquitin-specific protease inhibitors USP28, USP25, USP24 ALDH1A1 2167/4885MAPK1 2061/4885L3MBTL1 1885/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 ALDH1A1 1723/4885MAPK1 3295/4885L3MBTL1 4695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.