Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24372533 | 0.89 | ALDH1A1 (0.55) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL24372549 | 0.83 | LMNA (0.47) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL498454 | 0.82 | ALDH1A1 (0.68) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL24372557 | 0.81 | MGLL (0.44) | TDP1LMNA | |
| SCHEMBL24372545 | 0.81 | ALDH1A1 (0.46) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL11307628 | 0.80 | ALDH1A1 (0.66) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL20258860 | 0.78 | KMT2A (0.69) | CYP2C9CYP2C19ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL11137258 | 0.77 | ALDH1A1 (0.61) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL25527470 | 0.77 | FOLH1 (0.49) | ALDH1A1MAPK1L3MBTL1KMT2AMEN1 | |
| SCHEMBL21993645 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127286-A1 | LIGANDS FOR NANO-SIZED MATERIALS | MERCK PATENT GMBH (DE) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127286-A1 | LIGANDS FOR NANO-SIZED MATERIALS | L1CAM, EPCAM, SELPLG | CYP1A2 3581/4885CYP2C9 3260/4885CYP2C19 3474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.