Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24372602 | 0.93 | TAAR1 (0.44) | HDAC2HDAC1HSD11B1TAAR1FDFT1 | |
| SCHEMBL24372593 | 0.91 | SIGMAR1 (0.47) | HDAC2HDAC1SIGMAR1HDAC3HDAC4 | |
| SCHEMBL22004489 | 0.88 | HDAC2 (0.51) | HDAC2HDAC1SIGMAR1HSD11B1TAAR1 | |
| SCHEMBL12316354 | 0.86 | TAAR1 (0.47) | HSD11B1TAAR1MEN1ALDH1A1MAPT | |
| SCHEMBL15076231 | 0.85 | HSD11B1 (0.58) | HSD11B1RARBMEN1ALDH1A1RARA | |
| SCHEMBL24372435 | 0.84 | KCNH2 (0.46) | SIGMAR1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL12316356 | 0.82 | TAAR1 (0.42) | TAAR1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL24372592 | 0.82 | FFAR1 (0.50) | HDAC2HDAC1HSD11B1TAAR1FDFT1 | |
| SCHEMBL14063940 | 0.81 | RARB (0.57) | HSD11B1RARBMEN1ALDH1A1RARA | |
| SCHEMBL12386345 | 0.81 | HSD11B1 (0.58) | HSD11B1TAAR1RARBMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127286-A1 | LIGANDS FOR NANO-SIZED MATERIALS | MERCK PATENT GMBH (DE) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127286-A1 | LIGANDS FOR NANO-SIZED MATERIALS | L1CAM, EPCAM, SELPLG | HDAC2 4617/4885HDAC1 4342/4885SIGMAR1 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.