Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | STAT3 | P40763 | 2/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 6/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24372587 | 0.96 | TAAR1 (0.33) | HSD11B1TAAR1 | |
| SCHEMBL25866833 | 0.87 | HSD11B1 (0.39) | HSD11B1STAT3GPR3RARBMEN1 | |
| SCHEMBL14004029 | 0.86 | PDK2 (0.42) | HSD11B1STAT3MEN1ALDH1A1MAPT | |
| SCHEMBL14004037 | 0.86 | PDK2 (0.42) | HSD11B1STAT3MEN1ALDH1A1MAPT | |
| SCHEMBL24372726 | 0.86 | FOLH1 (0.35) | TAAR1 | |
| SCHEMBL25866841 | 0.86 | HSD11B1 (0.39) | HSD11B1STAT3GPR3RARBMEN1 | |
| SCHEMBL24372735 | 0.85 | MGLL (0.35) | HDAC1HDAC2STAT3RARB | |
| SCHEMBL24372554 | 0.85 | S1PR3 (0.41) | HDAC1HDAC2 | |
| SCHEMBL26226736 | 0.84 | GPR3 (0.39) | HSD11B1STAT3GPR3RARBMEN1 | |
| SCHEMBL25866855 | 0.84 | GPR3 (0.39) | HSD11B1STAT3GPR3RARBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127286-A1 | LIGANDS FOR NANO-SIZED MATERIALS | MERCK PATENT GMBH (DE) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127286-A1 | LIGANDS FOR NANO-SIZED MATERIALS | L1CAM, EPCAM, SELPLG | HSD11B1 4864/4885HDAC1 4342/4885HDAC2 4617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.