SCHEMBL2437345

SCHEMBL2437345

C=CC(=O)NC(O)CC(C)C

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.56
ALDH1A1 P00352 3/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
CYP2C19 P33261 1/20 0.34
ACACB O00763 2/20 0.34
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
PSMB5 P28074 2/20 0.32
KISS1R Q969F8 3/20 0.32
MAPT P10636 1/20 0.32
RNPEP Q9H4A4 1/20 0.31
SLC7A5 Q01650 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13751190 0.81 TSHR (0.58) TSHRALDH1A1MAPK1TDP1TAS1R3
SCHEMBL1065203 0.78 TSHR (0.54) TSHRALDH1A1MAPK1TDP1TAS1R3
SCHEMBL108995 0.78
SCHEMBL22868489 0.78 TSHR (0.54) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL8804418 0.76 TSHR (0.52) TSHRALDH1A1MAPK1TDP1TAS1R3
SCHEMBL21143017 0.76 TSHR (0.52) TSHRALDH1A1MAPK1TDP1TAS1R3
SCHEMBL8219449 0.76 TSHR (0.52) TSHRALDH1A1MAPK1TDP1TAS1R3
SCHEMBL8188102 0.76 ALDH1A1 (0.60) TSHRALDH1A1MEN1LMNAKMT2A
SCHEMBL1711240 0.76 ALDH1A1 (0.60) TSHRALDH1A1MEN1LMNAKMT2A
SCHEMBL27828839 0.76 ALDH1A1 (0.60) TSHRALDH1A1MEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023169566-A1 CATALYST FOR PHOTOCATALYTIC POLYMERIZATION REACTION, AND APPLICATION THEREOF 北京服装学院 2023-09-14 WO disclosed
EP-1905878-B1 Self-crosslinking vinyl acetate-ethylene polymeric binders for nonwoven webs WACKER CHEMICAL CORP (US) 2011-09-14 EP disclosed
EP-1589138-B1 Improvement in the wet tensile strength of nonwoven webs WACKER CHEMICAL CORP (US) 2009-07-22 EP disclosed
US-7485590-B2 Self-crosslinking vinyl acetate-ethylene polymeric binders for nonwoven webs WACKER CHEMICAL CORPORATION 2009-02-03 US disclosed
EP-1589139-B1 Nonwovens with binders of high wet/dry tensile strength ratio WACKER CHEMICAL CORP (US) 2009-01-14 EP disclosed
US-7427444-B2 Polymer emulsion coatings for cellulosic substrates with improved barrier properties AIR PRODUCTS POLYMERS, L.P. 2008-09-23 US disclosed
US-20080081530-A1 Self-crosslinking vinyl acetate-ethylene polymeric binders for nonwoven webs WACKER POLYMERS, L.P. 2008-04-03 US disclosed
EP-1905878-A2 Self-crosslinking vinyl acetate-ethylene polymeric binders for nonwoven webs AIR PRODUCTS POLYMERS, L.P. (US) 2008-04-02 EP disclosed
US-7297644-B2 Nonwoven binders with high wet/dry tensile strength ratio AIR PRODUCTS POLYMERS, L.P. (US) 2007-11-20 US disclosed
US-7285504-B2 Flushes, disperses and finally biodegrades, pre-moistened nonwoven wet wipe AIR PRODUCTS POLYMERS, L.P. (US) 2007-10-23 US disclosed
US-20050239359-A1 Wet tensile strength of nonwoven webs WACKER POLYMERS, L.P. 2005-10-27 US disclosed
US-20050239362-A1 Nonwoven binders with high wet/dry tensile strength ratio WACKER POLYMERS, L.P. 2005-10-27 US disclosed
EP-1589139-A1 Nonwovens with binders of high wet/dry tensile strength ratio AIR PRODUCTS POLYMERS, L.P. (US) 2005-10-26 EP disclosed
EP-1589138-A1 Improvement in the wet tensile strength of nonwoven webs AIR PRODUCTS POLYMERS, L.P. (US) 2005-10-26 EP disclosed
US-20050014013-A1 Polymer emulsion coatings for cellulosic substrates with improved barrier properties WACKER POLYMERS, L.P. 2005-01-20 US disclosed
EP-1498544-A1 Polymer emulsion coatings for cellulosic substrates with improved barrier properties AIR PRODUCTS POLYMERS, L.P. (US) 2005-01-19 EP disclosed
US-20040242106-A1 Nonwoven binders with high wet/dry tensile strength ratio WACKER POLYMERS, L.P. 2004-12-02 US disclosed
EP-1482081-A1 Nonwoven binders with high wet/dry tensile strength ratio AIR PRODUCTS POLYMERS, L.P. (US) 2004-12-01 EP disclosed
EP-0781359-A1 USE OF SOLVENT-RESISTANT TEXTILE BINDERS WACKER-CHEMIE GMBH (DE) 1997-07-02 EP disclosed
WO-1996008597-A1 SOLVENT-RESISTANT TEXTILE BINDER WACKER-CHEMIE GMBH (DE) 1996-03-21 WO disclosed