SCHEMBL1711240

SCHEMBL1711240

C=CC(=O)N[C@@H](CC(C)C)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.60
MEN1 O00255 1/20 0.56
LMNA P02545 1/20 0.56
KMT2A Q03164 1/20 0.56
MAPT P10636 1/20 0.53
TSHR P16473 1/20 0.52
FOLH1 Q04609 9/20 0.50
LAP3 P28838 3/20 0.47
NAALAD2 Q9Y3Q0 2/20 0.46
PLA2G2A P14555 2/20 0.45
PLA2G5 P39877 2/20 0.45
GRN P28799 1/20 0.45
SORT1 Q99523 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27828839 1.00 ALDH1A1 (0.60) ALDH1A1MEN1LMNAKMT2AMAPT
SCHEMBL8188102 1.00 ALDH1A1 (0.60) ALDH1A1MEN1LMNAKMT2AMAPT
Benzene SCHEMBL28285392 0.96 ALDH1A1 (0.56) ALDH1A1MEN1LMNAKMT2AMAPT
SCHEMBL8219449 0.85 TSHR (0.52) ALDH1A1MEN1LMNAKMT2AMAPT
SCHEMBL8373321 0.83 TSHR (0.50) ALDH1A1MEN1LMNAKMT2AMAPT
SCHEMBL8373322 0.83 TSHR (0.50) ALDH1A1MEN1LMNAKMT2AMAPT
SCHEMBL29820642 0.81 TAS1R3 (0.55) TSHRFOLH1
SCHEMBL21367972 0.81 TAS1R3 (0.55) TSHRFOLH1
SCHEMBL31139963 0.81 ALDH1A1 (0.47) ALDH1A1MEN1LMNAKMT2AMAPT
SCHEMBL4599325 0.80 TSHR (0.50) ALDH1A1MAPTTSHRFOLH1NAALAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118892583-B High-wet tissue adhesion anti-swelling conductive hydrogel and preparation method thereof 西安交通大学 2026-05-12 CN claimed
CN-115612014-B Biological tissue adhesive capable of being adhered when meeting water and preparation method thereof 西安交通大学 2024-02-13 CN claimed
CN-115612014-A Biological tissue adhesive capable of adhering immediately when meeting water and preparation method thereof 西安交通大学 2023-01-17 CN claimed
CN-115414520-A Self-gel styptic powder and preparation method and application thereof 西安交通大学 2022-12-02 CN claimed
CN-110684150-B Amino acid nano hydrogel and preparation method and application thereof 南方医科大学 2021-05-11 CN claimed
CN-112142911-A High-toughness hydrogel based on amino acid acrylamide derivative and preparation method thereof 西安交通大学 2020-12-29 CN claimed
CN-110684150-A Amino acid nano hydrogel and preparation method and application thereof 南方医科大学 2020-01-14 CN claimed
EP-1844022-B1 QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF HANMI SCIENCE CO LTD (KR) 2013-08-14 EP claimed
JP-2008525522-A 2008-07-17 JP claimed
US-20080009509-A1 Quinazoline Derivatives For Inhibiting Cancer Cell Growth And Method For The Preparation Thereof HANMI PHARM CO., LTD (KR) 2008-01-10 US claimed
EP-1844022-A1 QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF Hanmi Pharm. Co., Ltd. (KR) 2007-10-17 EP claimed
WO-2006071017-A1 QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF HANMI PHARM. CO., LTD. (KR) 2006-07-06 WO claimed
CN-118892583-B High-wet tissue adhesion anti-swelling conductive hydrogel and preparation method thereof 西安交通大学 2026-05-12 CN disclosed
CN-114096560-B Sugar purification 默克专利股份公司 2025-06-13 CN disclosed
CN-118892583-A High-wet tissue adhesion anti-swelling conductive hydrogel and preparation method thereof 西安交通大学 2024-11-05 CN disclosed
CN-114007737-B Antibody drug conjugate purification 默克专利股份公司 2024-07-05 CN disclosed
US-6046289-A FOR INHIBITING COAGULATION OF BLOOD PLATELETS, INHIBITING ADHESION OF ANIMAL CELLS, OR AS SUBSTRATE FOR CULTURING ANIMAL CELLS FUJIFILM CORPORATION (JP) 2000-04-04 US disclosed
EP-0488258-B1 Propenamide derivatives, polymers, copolymers and use thereof FUJI PHOTO FILM CO LTD (JP) 1996-04-17 EP disclosed
EP-0488258-A2 Propenamide derivatives, polymers, copolymers and use thereof FUJI PHOTO FILM CO., LTD. (JP) 1992-06-03 EP disclosed
US-4439545-A Acrylic copolymers of N-acryloylpolymethyleneimines or N-acryloyldialkylamides, N,N'-acryloyldiaminoalcanes and N-acryloylaminoacids (or esters) their preparation and use as cation exchangers SOCIETE D "EXPANSION SCIENTIFIQUE "EXPANSIA" (FR) 1984-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080009509-A1 Quinazoline Derivatives For Inhibiting Cancer Cell Growth And Method For The Preparation Thereof MKI67, NQO2, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 ALDH1A1 2222/4885MEN1 822/4885LMNA 3026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.