SCHEMBL8219449

SCHEMBL8219449

C=CC(=O)NC(CC(C)C)C(C)=O

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
ALDH1A1 P00352 3/20 0.46
MEN1 O00255 1/20 0.39
LMNA P02545 1/20 0.39
KMT2A Q03164 1/20 0.39
TAS1R3 Q7RTX0 3/20 0.37
TAS1R1 Q7RTX1 3/20 0.37
MAPT P10636 1/20 0.37
KISS1R Q969F8 4/20 0.36
MMP2 P08253 1/20 0.36
MMP3 P08254 1/20 0.36
MMP7 P09237 1/20 0.36
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
NOS3 P29474 4/20 0.35
NOS1 P29475 4/20 0.35
NOS2 P35228 4/20 0.35
FOLH1 Q04609 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8373322 0.87 TSHR (0.50) TSHRALDH1A1MEN1LMNAKMT2A
SCHEMBL8373321 0.87 TSHR (0.50) TSHRALDH1A1MEN1LMNAKMT2A
SCHEMBL1711240 0.85 ALDH1A1 (0.60) TSHRALDH1A1MEN1LMNAKMT2A
SCHEMBL27828839 0.85 ALDH1A1 (0.60) TSHRALDH1A1MEN1LMNAKMT2A
SCHEMBL8188102 0.85 ALDH1A1 (0.60) TSHRALDH1A1MEN1LMNAKMT2A
Benzene SCHEMBL28285392 0.81 ALDH1A1 (0.56) TSHRALDH1A1MEN1LMNAKMT2A
SCHEMBL21367972 0.81 TAS1R3 (0.55) TSHRTAS1R3TAS1R1NOS3NOS1
SCHEMBL29820642 0.81 TAS1R3 (0.55) TSHRTAS1R3TAS1R1NOS3NOS1
SCHEMBL12231521 0.80 TSHR (0.43) TSHRALDH1A1MEN1LMNAKMT2A
SCHEMBL21368435 0.79 PPID (0.46) TSHRTAS1R3TAS1R1NOS3NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6024895-A COMPRISING SOLUBLE, ELECTRICALLY CONDUCTING POLYMER HAVING SULFONIC ACID GROUP AND/OR CARBOXYL GROUP AND THERMALLY CROSS-LINKABLE OR ULTRAVIOLET- OR ELECTRON BEAM-CROSS-LINKABLE RESIN OR PAINT MITSUBISHI RAYON CO., LTD. (JP) 2000-02-15 US disclosed
EP-0844284-A1 CROSS-LINKABLE CONDUCTIVE COMPOSITION, CONDUCTOR, AND PROCESS FOR FORMING THE SAME NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1998-05-27 EP disclosed
EP-0837112-A2 Cross-linkable, electrically conductive composition, electric conductor and process for forming the same NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1998-04-22 EP disclosed
EP-0505972-B1 Process for producing styrenic copolymer IDEMITSU KOSAN CO (JP) 1997-06-11 EP disclosed
EP-0490269-B1 Graft copolymer and process for producing the same IDEMITSU KOSAN CO (JP) 1996-02-28 EP disclosed
US-5250629-A Graft polymerization of styrene and ethylenically unsaturated monomer using transition metal catalysts, organoaluminum compounds; films, packaging, automobile parts IDEMITSU KOSAN CO., LTD. (JP) 1993-10-05 US disclosed
EP-0505972-A2 Process for producing styrenic copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed