SCHEMBL2437391

SCHEMBL2437391

CC(C)=CCC(C)(CC=C(C)C)C(=O)C(C)C

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.33
TSHR P16473 2/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
KMT2A Q03164 1/20 0.33
ALOX15 P16050 2/20 0.32
GGPS1 O95749 3/20 0.31
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL81453 0.83 MAPK1 (0.37) MAPK1L3MBTL1TSHRMEN1ALDH1A1
SCHEMBL2441710 0.77 MAPK1 (0.41) MAPK1L3MBTL1TSHRMEN1ALDH1A1
SCHEMBL21800956 0.75 TSHR (0.31) MAPK1L3MBTL1TSHRMEN1ALDH1A1
SCHEMBL17106318 0.71 MAPK1 (0.38) MAPK1L3MBTL1TSHRMEN1ALDH1A1
SCHEMBL2440553 0.71 MAPK1 (0.38) MAPK1L3MBTL1TSHRMEN1ALDH1A1
SCHEMBL17106316 0.71 MAPK1 (0.38) MAPK1L3MBTL1TSHRMEN1ALDH1A1
SCHEMBL17106320 0.71 MAPK1 (0.38) MAPK1L3MBTL1TSHRMEN1ALDH1A1
SCHEMBL17106210 0.70 MAPK1 (0.37) MAPK1L3MBTL1TSHRMEN1ALDH1A1
SCHEMBL13307718 0.69 MAPK1 (0.34) MAPK1L3MBTL1TSHRMEN1ALDH1A1
SCHEMBL2441530 0.69 MAPK1 (0.34) MAPK1L3MBTL1TSHRMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102300550-A Perfume systems 2011-12-28 CN claimed
EP-2362765-A2 PERFUME SYSTEMS The Procter & Gamble Company (US) 2011-09-07 EP claimed
WO-2010065446-A2 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY (US) 2010-06-10 WO claimed
US-20100137178-A1 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY 2010-06-03 US claimed
EP-2362765-B1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2020-04-08 EP disclosed
US-8431520-B2 Perfume systems THE PROCTER & GAMBLE COMPANY (US) 2013-04-30 US disclosed
US-8431520-B2 Perfume systems THE PROCTER & GAMBLE COMPANY (US) 2013-04-30 US disclosed
US-8431520-B2 Perfume systems THE PROCTER & GAMBLE COMPANY (US) 2013-04-30 US disclosed
US-20130012422-A1 PERFUME SYSTEMS SMETS JOHAN (BE) 2013-01-10 US disclosed
US-20130012422-A1 PERFUME SYSTEMS SMETS JOHAN (BE) 2013-01-10 US disclosed
US-20130012422-A1 PERFUME SYSTEMS SMETS JOHAN (BE) 2013-01-10 US disclosed
US-20100137178-A1 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY 2010-06-03 US disclosed
US-20100137178-A1 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY 2010-06-03 US disclosed
US-20100137178-A1 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY 2010-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130012422-A1 PERFUME SYSTEMS TRPA1, PORCN, PLIN5 MAPK1 4486/4885L3MBTL1 4836/4885TSHR 4772/4885
US-20100137178-A1 PERFUME SYSTEMS TRPA1, PORCN, PLIN5 MAPK1 4486/4885L3MBTL1 4836/4885TSHR 4772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.