SCHEMBL2437397

SCHEMBL2437397

CCCCCCCCOc1ccc(-c2cccc(S)c2-c2ccc(OCCCCCCCC)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.50
NR5A1 Q13285 1/20 0.47
TP53 P04637 2/20 0.47
TSHR P16473 2/20 0.47
LTA4H P09960 1/20 0.46
PLA2G4B P0C869 2/20 0.46
PTPN11 Q06124 1/20 0.45
NPC1 O15118 1/20 0.43
LMNA P02545 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
ALOX15 P16050 1/20 0.43
RAB9A P51151 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CYP2D6 P10635 2/20 0.43
CYP3A4 P08684 1/20 0.43
THRA P10827 1/20 0.43
THRB P10828 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP19A1 P11511 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9333532 1.00 RARB (0.50) RARBNR5A1TP53TSHRLTA4H
Ethane SCHEMBL3418824 0.99 RARB (0.49) RARBNR5A1TP53TSHRLTA4H
Methane SCHEMBL3419259 0.99 RARB (0.49) RARBNR5A1TP53TSHRLTA4H
SCHEMBL3419240 0.95 RARB (0.46) RARBNR5A1TP53TSHRLTA4H
SCHEMBL3422015 0.94 RARB (0.45) RARBNR5A1TP53TSHRLTA4H
Trifluoromethanesulfonic Acid SCHEMBL3740925 0.87 RARB (0.45) RARBNR5A1TP53TSHRPLA2G4B
Trifluoromethanesulfonic Acid SCHEMBL4620193 0.87 RARB (0.45) RARBNR5A1TP53TSHRPLA2G4B
Trifluoromethanesulfonic Acid SCHEMBL4620136 0.87 RARB (0.45) RARBNR5A1TP53TSHRPLA2G4B
SCHEMBL29110819 0.87 LTA4H (0.54) RARBNR5A1TP53TSHRLTA4H
SCHEMBL28194312 0.85 LTA4H (0.57) RARBNR5A1TP53TSHRLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2078028-B1 PHOTOACTIVE COMPOUNDS AZ ELECTRONIC MATERIALS USA (US) 2011-09-07 EP claimed