Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 4/20 | 0.38 |
| ▸ | CASP1 | P29466 | 3/20 | 0.38 |
| ▸ | CASP7 | P55210 | 3/20 | 0.38 |
| ▸ | CASP6 | P55212 | 3/20 | 0.38 |
| ▸ | CASP8 | Q14790 | 3/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | YAP1 | P46937 | 3/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | PSMB11 | A5LHX3 | 3/20 | 0.37 |
| ▸ | PSMA7 | O14818 | 3/20 | 0.37 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.37 |
| ▸ | PSMA1 | P25786 | 3/20 | 0.37 |
| ▸ | PSMA2 | P25787 | 3/20 | 0.37 |
| ▸ | PSMA3 | P25788 | 3/20 | 0.37 |
| ▸ | PSMA4 | P25789 | 3/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27217471 | 1.00 | ITGB1 (0.40) | ITGB1ITGA4UBE2NCASP3CASP1 | |
| SCHEMBL27217462 | 1.00 | ITGB1 (0.40) | ITGB1ITGA4UBE2NCASP3CASP1 | |
| SCHEMBL27217454 | 0.95 | ITGB1 (0.39) | ITGB1ITGA4UBE2NCASP3CASP1 | |
| SCHEMBL27217459 | 0.95 | ITGB1 (0.39) | ITGB1ITGA4UBE2NCASP3CASP1 | |
| SCHEMBL24374731 | 0.95 | ITGB1 (0.39) | ITGB1ITGA4UBE2NCASP3CASP1 | |
| SCHEMBL24374707 | 0.95 | ITGB1 (0.39) | ITGB1ITGA4UBE2NCASP3CASP1 | |
| SCHEMBL24374510 | 0.95 | ITGB1 (0.39) | ITGB1ITGA4UBE2NCASP3CASP1 | |
| SCHEMBL24374728 | 0.94 | ITGB1 (0.38) | ITGB1ITGA4UBE2NCASP3CASP1 | |
| SCHEMBL22556028 | 0.94 | ITGB1 (0.38) | ITGB1ITGA4UBE2NCASP3CASP1 | |
| SCHEMBL22556032 | 0.94 | ITGB1 (0.38) | ITGB1ITGA4UBE2NCASP3CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158375-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | Azura Ophthalmics Ltd. (IL) | 2024-05-16 | — | — | US | disclosed |
| EP-4232458-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | AZURA OPHTHALMICS LTD (IL) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022084747-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | Azura Ophthalmics Ltd. (IL) | 2022-04-28 | — | — | WO | disclosed |
| WO-2022084747-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | Azura Ophthalmics Ltd. (IL) | 2022-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158375-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | MPO, MUC1, CRYAB | ITGB1 1385/4885ITGA4 1271/4885UBE2N 1363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.