Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29323570 | 0.91 | LMNA (0.52) | LMNAMEN1KMT2AALDH1A1TSHR | |
| Propylamine SCHEMBL28089563 | 0.82 | DNM1 (0.48) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL11339846 | 0.82 | DNM1 (0.60) | LMNADNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL14840172 | 0.82 | DNM1 (0.60) | LMNADNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL13631066 | 0.82 | DNM1 (0.60) | LMNADNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL24641257 | 0.82 | DNM1 (0.60) | LMNADNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL5076671 | 0.82 | DNM1 (0.60) | LMNADNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL14840252 | 0.82 | DNM1 (0.60) | LMNADNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL21862180 | 0.82 | DNM1 (0.60) | LMNADNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL14840101 | 0.82 | DNM1 (0.60) | LMNADNM1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3988537-A1 | BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | Alnylam Pharmaceuticals, Inc. (US) | 2022-04-27 | — | — | EP | disclosed |