Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.38 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PPARD | Q03181 | 6/20 | 0.38 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24375710 | 0.91 | LMNA (0.44) | LMNAFFAR4FFAR1TSHRALDH1A1 | |
| SCHEMBL1904679 | 0.88 | TSHR (0.53) | LMNAFFAR4FFAR1PPARGTSHR | |
| SCHEMBL1901451 | 0.88 | TSHR (0.53) | LMNAFFAR4FFAR1PPARGTSHR | |
| SCHEMBL1905194 | 0.88 | TSHR (0.53) | LMNAFFAR4FFAR1PPARGTSHR | |
| SCHEMBL1901214 | 0.88 | TSHR (0.53) | LMNAFFAR4FFAR1PPARGTSHR | |
| SCHEMBL1907176 | 0.88 | TSHR (0.53) | LMNAFFAR4FFAR1PPARGTSHR | |
| SCHEMBL3188281 | 0.86 | CES2 (0.50) | FFAR4FFAR1CES2CES1GPR84 | |
| SCHEMBL1276219 | 0.86 | CES2 (0.50) | FFAR4FFAR1CES2CES1GPR84 | |
| SCHEMBL21834650 | 0.86 | CES2 (0.50) | FFAR4FFAR1CES2CES1GPR84 | |
| SCHEMBL1261681 | 0.86 | CES2 (0.50) | FFAR4FFAR1CES2CES1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400491-A1 | NOVEL LIPIDS USED FOR NUCLEIC ACID DELIVERY AND LIPID NANOPARTICLE COMPOSITION | Themedium Therapeutics Co., Ltd (CN) | 2024-07-17 | — | — | EP | disclosed |