Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.69 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.62 |
| ▸ | MET | P08581 | 1/20 | 0.59 |
| ▸ | AXL | P30530 | 1/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.51 |
| ▸ | CDK2 | P24941 | 5/20 | 0.51 |
| ▸ | DRD4 | P21917 | 4/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27500636 | 0.89 | GPR84 (0.63) | GPR84MTNR1AMETAXLCCNE1 | |
| SCHEMBL2217980 | 0.87 | GPR84 (0.76) | GPR84MTNR1AMETAXLCCNE1 | |
| SCHEMBL7010590 | 0.86 | GPR84 (0.73) | GPR84MTNR1AMETAXLCCNE1 | |
| SCHEMBL3888485 | 0.83 | GPR84 (0.69) | GPR84MTNR1AMETAXLCCNE1 | |
| SCHEMBL32669457 | 0.83 | GPR84 (0.69) | GPR84MTNR1AMETAXLCCNE1 | |
| SCHEMBL7504761 | 0.83 | GPR84 (0.69) | GPR84MTNR1AMETAXLCCNE1 | |
| SCHEMBL738162 | 0.83 | GPR84 (0.69) | GPR84MTNR1AMETAXLCCNE1 | |
| SCHEMBL31036176 | 0.83 | GPR84 (0.69) | GPR84MTNR1AMETAXLCCNE1 | |
| SCHEMBL857145 | 0.83 | GPR84 (0.69) | GPR84MTNR1AMETAXLCCNE1 | |
| SCHEMBL27911675 | 0.82 | GPR84 (1.00) | GPR84MTNR1AMETAXLCCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026103873-A1 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL USE THEREOF | 杭州百新生物医药科技有限公司 | 2026-05-21 | — | — | WO | disclosed |
| CN-119948035-A | Compounds useful for modulating AhR signaling | 捷豹治疗有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-102046633-B | Substituted spirocyclic cyclohexane derivatives | GRUENENTHAL GMBH | 2015-03-25 | — | — | CN | disclosed |
| CN-101490055-B | Spirocyclic azaindole derivatives | GRUENENTHAL GMBH | 2013-10-16 | — | — | CN | disclosed |
| EP-2041142-B1 | SPIROCYCLIC AZAINDOLE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2013-10-09 | — | — | EP | disclosed |
| US-8399503-B2 | Spirocyclic azaindole derivatives | GRUENENTHAL GMBH (DE) | 2013-03-19 | — | — | US | disclosed |
| US-8293758-B2 | Substituted spirocyclic cyclohexane derivatives | GRUNENTHAL GMBH (DE) | 2012-10-23 | — | — | US | disclosed |
| EP-2260042-B1 | SUBSTITUTED SPIROCYCLIC CYCLOHEXANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2011-09-21 | — | — | EP | disclosed |
| CN-102046633-A | Substituted spirocyclic cyclohexane derivatives | GRUENENTHAL GMBH | 2011-05-04 | — | — | CN | disclosed |
| EP-2260042-A1 | SUBSTITUTED SPIROCYCLIC CYCLOHEXANE DERIVATIVES | Grünenthal GmbH (DE) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009118173-A1 | SUBSTITUTED SPIROCYCLIC CYCLOHEXANE DERIVATIVES | Grünenthal GmbH (DE) | 2009-10-01 | — | — | WO | disclosed |
| US-20090247561-A1 | SUBSTITUTED SPIROCYCLIC CYCLOHEXANE DERIVATIVES | GRUNENTHAL GMBH (DE) | 2009-10-01 | — | — | US | disclosed |
| CN-101490055-A | Spirocyclic azaindole derivatives | GRUENENTHAL GMBH (DE) | 2009-07-22 | — | — | CN | disclosed |
| US-20090156593-A1 | Spirocyclic Azaindole Derivatives | GRUNENTHAL GMBH (DE) | 2009-06-18 | — | — | US | disclosed |
| EP-2041142-A1 | SPIROCYCLIC AZAINDOLE DERIVATIVES | Grünenthal GmbH (DE) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008009416-A1 | SPIROCYCLIC AZAINDOLE DERIVATIVES | Grünenthal GmbH (DE) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156593-A1 | Spirocyclic Azaindole Derivatives | AZI2, TPMT, AADAC | GPR84 3141/4885MTNR1A 179/4885MET 3817/4885 |
| US-20090247561-A1 | SUBSTITUTED SPIROCYCLIC CYCLOHEXANE DERIVATIVES | OPRL1, OPRK1, OPRD1 | GPR84 94/4885MTNR1A 205/4885MET 800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.