Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLLT3 | P42568 | 2/20 | 0.65 |
| ▸ | MLLT1 | Q03111 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | RARA | P10276 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | RARG | P13631 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | CDH1 | P12830 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PTPRA | P18433 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24376314 | 0.88 | MLLT3 (0.64) | MLLT3MLLT1ALDH1A1PTPN1HPGD | |
| SCHEMBL24376589 | 0.86 | MLLT1 (0.64) | MLLT3MLLT1ALDH1A1HPGDMAPT | |
| SCHEMBL24376430 | 0.86 | MLLT1 (0.71) | MLLT3MLLT1ALDH1A1HPGDMAPT | |
| SCHEMBL11902392 | 0.80 | ALDH1A1 (0.62) | ALDH1A1PTPN1HPGDMAPTRECQL | |
| SCHEMBL27101315 | 0.79 | ALDH1A1 (0.64) | ALDH1A1PTPN1HPGDMAPTRECQL | |
| SCHEMBL29622112 | 0.76 | MLLT3 (0.47) | MLLT3MLLT1ALDH1A1HPGDMAPT | |
| SCHEMBL22778856 | 0.76 | ALDH1A1 (0.64) | MLLT3MLLT1ALDH1A1PTPN1HPGD | |
| SCHEMBL17731947 | 0.76 | ALDH1A1 (0.64) | ALDH1A1PTPN1HPGDMAPTRECQL | |
| SCHEMBL30645203 | 0.76 | ALDH1A1 (0.64) | ALDH1A1PTPN1HPGDMAPTRECQL | |
| SCHEMBL17731960 | 0.75 | ALDH1A1 (0.65) | ALDH1A1PTPN1HPGDMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022086937-A9 | HETEROBIFUNCTIONAL COMPOUNDS AS DEGRADERS OF ENL | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-02-02 | — | — | WO | disclosed |
| WO-2022086937-A1 | HETEROBIFUNCTIONAL COMPOUNDS AS DEGRADERS OF ENL | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2022-04-28 | — | — | WO | disclosed |