Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLLT3 | P42568 | 2/20 | 0.47 |
| ▸ | MLLT1 | Q03111 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29622224 | 0.93 | MLLT3 (0.45) | MLLT3MLLT1HPGDMAPTLMNA | |
| SCHEMBL29622336 | 0.78 | HTT (0.46) | MAPTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL24376591 | 0.76 | MLLT3 (0.65) | MLLT3MLLT1HPGDMAPTLMNA | |
| SCHEMBL29622084 | 0.74 | HTT (0.42) | HPGDMAPTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL17846625 | 0.70 | LMNA (0.61) | MAPTLMNASMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL24376316 | 0.70 | MLLT3 (0.49) | MLLT3MLLT1HPGDMAPTLMNA | |
| SCHEMBL10827358 | 0.69 | LMNA (0.60) | MAPTLMNASMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL24376589 | 0.69 | MLLT1 (0.64) | MLLT3MLLT1HPGDMAPTLMNA | |
| SCHEMBL25983314 | 0.69 | LMNA (0.56) | MAPTLMNASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL14772158 | 0.68 | LMNA (0.65) | MAPTLMNASMN1; SMN2RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022086937-A9 | HETEROBIFUNCTIONAL COMPOUNDS AS DEGRADERS OF ENL | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-02-02 | — | — | WO | disclosed |
| WO-2022086937-A1 | HETEROBIFUNCTIONAL COMPOUNDS AS DEGRADERS OF ENL | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2022-04-28 | — | — | WO | disclosed |