Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | MLYCD | O95822 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24376263 | 0.76 | KDM4E (0.37) | KDM4EMAPTKMT2AMEN1ALOX15 | |
| SCHEMBL9225568 | 0.68 | HDAC4 (0.38) | KDM4EMAPTKMT2AMEN1ALOX15 | |
| SCHEMBL5608026 | 0.65 | KDM4E (0.59) | KDM4EMAPTKMT2AMEN1ALOX15 | |
| SCHEMBL30032961 | 0.64 | MAPT (0.39) | KDM4EMAPTKMT2AMEN1ALOX15 | |
| SCHEMBL28051888 | 0.63 | KDM4E (0.48) | KDM4EMAPTKMT2AMEN1ALOX15 | |
| SCHEMBL30032278 | 0.62 | MAPT (0.40) | KDM4EMAPTKMT2AMEN1ALOX15 | |
| SCHEMBL11035853 | 0.62 | KDM4E (0.61) | KDM4EMAPTKMT2AMEN1ALOX15 | |
| SCHEMBL9330315 | 0.62 | KDM4E (0.43) | KDM4EMAPTKMT2AMEN1ALOX15 | |
| SCHEMBL9548196 | 0.61 | KDM4E (0.72) | KDM4EMAPTKMT2AMEN1ALOX15 | |
| SCHEMBL5078984 | 0.61 | KDM4E (0.39) | KDM4EMAPTKMT2AMEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087373-A1 | METHODS OF MAKING NICOTINIC ACID DERIVATIVES | VERTELLUS HOLDINGS LLC (US) | 2022-04-28 | — | — | WO | disclosed |