Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24376263 | 0.69 | KDM4E (0.37) | HDAC4HDAC6ADORA2BKDM4ELMNA | |
| SCHEMBL24376720 | 0.68 | KDM4E (0.36) | HDAC4HDAC6ADORA2BKDM4ELMNA | |
| SCHEMBL3760345 | 0.67 | HDAC4 (0.36) | HDAC4HDAC6ADORA2BKDM4ELMNA | |
| SCHEMBL31190876 | 0.66 | KDM4E (0.45) | KDM4ELMNAALDH1A1GAAPOLB | |
| SCHEMBL9726284 | 0.64 | KDM4E (0.62) | ADORA2BKDM4ELMNAALDH1A1GAA | |
| SCHEMBL9726347 | 0.62 | ADORA2B (0.48) | ADORA2BKDM4ELMNAALDH1A1GAA | |
| SCHEMBL18501088 | 0.62 | HDAC4 (0.38) | HDAC4HDAC6ADORA2BKDM4ELMNA | |
| SCHEMBL4739182 | 0.62 | HDAC4 (0.41) | HDAC4HDAC6ADORA2BKDM4ELMNA | |
| SCHEMBL9305990 | 0.62 | LMNA (0.43) | KDM4ELMNAALDH1A1GAAPOLB | |
| SCHEMBL4915483 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405865-A | Pyrethroid esters | ROUSSEL-UCLAF (FR) | 1995-04-11 | — | — | US | disclosed |