Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24376720 | 0.76 | KDM4E (0.36) | KDM4EMAPTKMT2AMEN1ALOX15 | |
| SCHEMBL9225568 | 0.69 | HDAC4 (0.38) | KDM4EMAPTKMT2AMEN1ALOX15 | |
| SCHEMBL5608026 | 0.66 | KDM4E (0.59) | KDM4EMAPTKMT2AMEN1ALOX15 | |
| SCHEMBL30032278 | 0.63 | MAPT (0.40) | KDM4EMAPTKMT2AMEN1ALOX15 | |
| SCHEMBL11035853 | 0.63 | KDM4E (0.61) | KDM4EMAPTKMT2AMEN1ALOX15 | |
| SCHEMBL20263547 | 0.63 | KDM4E (0.49) | KDM4EMAPTKMT2AMEN1ALOX15 | |
| SCHEMBL234027 | 0.63 | KDM4E (0.55) | KDM4EMAPTKMT2AMEN1ALOX15 | |
| SCHEMBL28283233 | 0.63 | KDM4E (0.55) | KDM4EMAPTKMT2AMEN1ALOX15 | |
| SCHEMBL9548196 | 0.62 | KDM4E (0.72) | KDM4EMAPTKMT2AMEN1ALOX15 | |
| SCHEMBL5078984 | 0.62 | KDM4E (0.39) | KDM4EMAPTKMT2AMEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240002341-A1 | METHODS OF MAKING NICOTINIC ACID DERIVATIVES | AURORIUM HOLDINGS LLC | 2024-01-04 | — | — | US | disclosed |
| CN-116635369-A | Process for preparing nicotinic acid derivatives | 弗特鲁斯控股有限责任公司 | 2023-08-22 | — | — | CN | disclosed |
| WO-2022087373-A1 | METHODS OF MAKING NICOTINIC ACID DERIVATIVES | VERTELLUS HOLDINGS LLC (US) | 2022-04-28 | — | — | WO | disclosed |
| WO-2022087373-A1 | METHODS OF MAKING NICOTINIC ACID DERIVATIVES | VERTELLUS HOLDINGS LLC (US) | 2022-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240002341-A1 | METHODS OF MAKING NICOTINIC ACID DERIVATIVES | NAPRT, NNMT, NAMPT | KDM4E 2875/4885MAPT 1698/4885KMT2A 1885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.