Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3412296 | 0.81 | KDM4E (0.46) | KDM4EKMT2AMEN1MAPTALOX15 | |
| SCHEMBL9726323 | 0.78 | ADORA2B (0.50) | KDM4EKMT2AMEN1MAPTALOX15 | |
| SCHEMBL9726284 | 0.77 | KDM4E (0.62) | KDM4EKMT2AMEN1MAPTALOX15 | |
| SCHEMBL9548196 | 0.77 | KDM4E (0.72) | KDM4EKMT2AMEN1MAPTALOX15 | |
| SCHEMBL95164 | 0.76 | KDM4E (1.00) | KDM4EKMT2AMEN1MAPTALOX15 | |
| SCHEMBL9726347 | 0.76 | ADORA2B (0.48) | KDM4EKMT2AMEN1MAPTALOX15 | |
| SCHEMBL10509439 | 0.75 | ADORA2B (0.50) | KDM4EMAPTADORA2BLMNAALDH1A1 | |
| SCHEMBL20654739 | 0.73 | KDM4E (0.67) | KDM4EKMT2AMEN1MAPTALOX15 | |
| SCHEMBL9726271 | 0.72 | ALDH1A1 (0.64) | KDM4EMAPTADORA2BLMNAALDH1A1 | |
| SCHEMBL10507556 | 0.72 | ADORA2B (0.48) | KDM4EMAPTADORA2BLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135491-A1 | Herbicidal 2,6-bis-fluoromethyl-dihydropyridine-3,5-dicarboxylic acid esters | MONSANTO COMPANY (US) | 1985-03-27 | — | — | EP | disclosed |