Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10191930 | 0.78 | TSHR (0.33) | TP53TSHRPTK2FFAR1 | |
| SCHEMBL5628771 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2ALMNAMEN1TP53 | |
| SCHEMBL20924859 | 0.74 | KMT2A (0.40) | SMN1; SMN2KMT2ALMNAMEN1TP53 | |
| SCHEMBL12475080 | 0.74 | SMN1; SMN2 (0.47) | SMN1; SMN2KMT2ALMNAMEN1TP53 | |
| SCHEMBL5169888 | 0.71 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL21663012 | 0.69 | FFAR1 (0.32) | SMN1; SMN2FFAR1 | |
| SCHEMBL24376698 | 0.69 | ALDH1A1 (0.58) | SMN1; SMN2LMNATSHRPOLBMAPT | |
| SCHEMBL12267885 | 0.68 | MAPT (0.45) | SMN1; SMN2KMT2ALMNAMEN1TP53 | |
| SCHEMBL18234241 | 0.68 | FFAR1 (0.34) | NPSR1KDM4EGAARECQLFFAR1 | |
| SCHEMBL17372035 | 0.67 | KMT2A (0.42) | SMN1; SMN2KMT2ALMNAMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127255-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (GB) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127255-A1 | HERBICIDAL COMPOUNDS | DDT, HDHD5, HPD | SMN1; SMN2 4663/4885KMT2A 991/4885LMNA 4081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.