SCHEMBL243768

SCHEMBL243768

O=CNNc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
TDP1 Q9NUW8 4/20 0.55
CTSD P07339 1/20 0.55
TSHR P16473 4/20 0.43
CYP3A4 P08684 2/20 0.43
ALOX5 P09917 2/20 0.43
GAA P10253 2/20 0.42
MAPT P10636 1/20 0.42
PTGS2 P35354 3/20 0.41
HSD17B10 Q99714 2/20 0.41
EPHX1 P07099 2/20 0.40
ADH1B P00325 1/20 0.39
ADH1C P00326 1/20 0.39
ADH1A P07327 1/20 0.39
ADH7 P40394 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
PTGS1 P23219 1/20 0.39
SLC6A2 P23975 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27814664 0.86 PTPN1 (0.44) ALDH1A1TDP1CTSDMAPTSMN1; SMN2
SCHEMBL28079989 0.85 ALDH1A1 (0.52) ALDH1A1TDP1CTSDTSHRCYP3A4
SCHEMBL10797576 0.84 SMN1; SMN2 (0.63) TSHRMAPTEPHX1TP53EPHX2
SCHEMBL9174022 0.82 ALDH1A1 (0.61) ALDH1A1TDP1CYP3A4GAAMAPT
SCHEMBL27820491 0.81 MGLL (0.52) ALDH1A1
SCHEMBL10356292 0.81 PGR (0.49) ALDH1A1TSHRSMN1; SMN2TGM2
SCHEMBL9785901 0.78 NPC1 (0.51) ALDH1A1TDP1CYP3A4GAAMAPT
SCHEMBL11309583 0.78 GAA (0.60) ALDH1A1TDP1CYP3A4GAAMAPT
SCHEMBL8761975 0.78 HTT (0.55) ALDH1A1ADH1BADH1CADH1AADH7
SCHEMBL17550794 0.77 KMT2A (0.65) ALDH1A1MAPTSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 497 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107372496-B Application of phenylhydrazino ketone compound as agricultural bactericide 华中师范大学 2021-01-15 CN claimed
CN-107478706-A The titration method of peroxide value in a kind of dried emulsifier under nitrogen guard mode 浙江圣兆药物科技股份有限公司 2017-12-15 CN claimed
CN-107372496-A Phenylhydrazino ketone compounds are in the purposes as disinfectant use in agriculture 华中师范大学 2017-11-24 CN claimed
CN-104897895-B The magnetic immunochemiluminescence detection kit of a kind of gentamicin and application thereof 北京勤邦生物技术有限公司 2016-08-24 CN claimed
CN-104897895-A Gentamycin magnetic immunochemiluminescence detection kit and application thereof BEIJING KWINBON BIOTECH CO LTD 2015-09-09 CN claimed
EP-1932844-B1 CROSS-LINKED CYCLIC AMINE COMPOUNDS AND AGENTS FOR PEST CONTROL NIPPON SODA CO (JP) 2015-09-02 EP claimed
CN-102177205-B Adhesive composition and method of adhesion DENKI KAGAKU KOGYO KK 2013-09-18 CN claimed
CN-102617553-A Agricultural ryanodine receptor activator and preparation method and application thereof INST PLANT PROTECTION IPP CAAS 2012-08-01 CN claimed
US-8084613-B2 Tetrazoyloxime derivative and plant disease control agent NIPPON SODA CO., LTD. (JP) 2011-12-27 US claimed
EP-1947098-B1 CYCLIC AMINE COMPOUNDS AND PEST CONTROL AGENT NIPPON SODA CO (JP) 2011-11-30 EP claimed
EP-0472925-A1 Substituted pyridins BAYER AG (DE) 1992-03-04 EP claimed
EP-0473209-A1 Method of making direct-positive computer output images AGFA-GEVAERT N.V. (BE) 1992-03-04 EP claimed
EP-0468104-A1 Light-sensitive silver halide material for making direct-positive images AGFA-GEVAERT N.V. (BE) 1992-01-29 EP claimed
EP-0459243-A2 Substituted Azines BAYER AG (DE) 1991-12-04 EP claimed
EP-0451653-A2 Naphthalene derivatives BAYER AG (DE) 1991-10-16 EP claimed
US-4971889-A Spectral sensitizing dye containnig a hydrazine residue FUJI PHOTO FILM CO., LTD. (JP) 1990-11-20 US claimed
EP-0357082-A2 Silver halide photographic emulsions FUJI PHOTO FILM CO., LTD. (JP) 1990-03-07 EP claimed
US-4287330-A Accelerator for curable compositions LOCTITE CORPORATION (US) 1981-09-01 US claimed
US-4180640-A HYDRAZIDE DERIVATIVES LOCTITE CORPORATION (US) 1979-12-25 US claimed
US-4041072-A PSYCHOTROPIC AGENTS DELALANDE S. A. (FR) 1977-08-09 US claimed