Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.36 |
| ▸ | DAO | P14920 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313465 | 0.71 | — | — | |
| SCHEMBL67859 | 0.69 | LMNA (0.58) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL10032702 | 0.68 | TYR (0.51) | TYRCA1CA2DAOKDM4E | |
| SCHEMBL71456 | 0.66 | LMNA (0.56) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL13485432 | 0.66 | TYR (0.36) | LMNATYRDAOTP53CYP1A2 | |
| SCHEMBL28217167 | 0.66 | — | — | |
| SCHEMBL13773186 | 0.64 | LMNA (0.54) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL11144707 | 0.64 | LMNA (0.54) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL10328545 | 0.64 | FABP3 (0.41) | KDM4E | |
| Bicarbonate SCHEMBL11611377 | 0.64 | LMNA (0.48) | LMNATRPA1CHRM1SLC6A2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127255-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (GB) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127255-A1 | HERBICIDAL COMPOUNDS | DDT, HDHD5, HPD | LMNA 4081/4885TRPA1 1581/4885CHRM1 1318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.