Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24377521 | 0.77 | TP53 (0.37) | TP53IDH1ALDH1A1 | |
| SCHEMBL21912376 | 0.77 | TP53 (0.41) | TP53ALDH1A1 | |
| SCHEMBL24377568 | 0.71 | TP53 (0.33) | TP53 | |
| SCHEMBL13553448 | 0.68 | PER2 (0.44) | TP53IDH1ALDH1A1 | |
| SCHEMBL13218347 | 0.68 | PER2 (0.44) | TP53IDH1ALDH1A1 | |
| SCHEMBL13553452 | 0.67 | PER2 (0.46) | TP53ALDH1A1 | |
| SCHEMBL24171087 | 0.64 | TP53 (0.36) | TP53ALDH1A1 | |
| SCHEMBL19369048 | 0.62 | LMNA (0.39) | TP53ALDH1A1 | |
| SCHEMBL7127280 | 0.61 | PIK3CD (0.31) | — | |
| SCHEMBL7127272 | 0.61 | PIK3CD (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022086986-A1 | TREATMENT OF HEMATOLOGICAL MALIGNANCIES WITH INHIBITORS OF MENIN | KURA ONCOLOGY, INC. (US) | 2022-04-28 | — | — | WO | disclosed |