Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20847147 | 0.77 | TP53 (0.36) | TP53 | |
| SCHEMBL19369325 | 0.76 | TP53 (0.35) | TP53 | |
| SCHEMBL21912376 | 0.75 | TP53 (0.41) | TP53 | |
| SCHEMBL20846885 | 0.75 | TP53 (0.34) | TP53 | |
| SCHEMBL22200199 | 0.73 | TP53 (0.33) | TP53 | |
| SCHEMBL24377761 | 0.71 | TP53 (0.34) | TP53 | |
| SCHEMBL19369124 | 0.71 | DRD2 (0.40) | — | |
| SCHEMBL16264635 | 0.69 | MEN1 (0.40) | TP53 | |
| SCHEMBL20400359 | 0.67 | MMP1 (0.45) | — | |
| SCHEMBL19369171 | 0.66 | TP53 (0.32) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022086986-A1 | TREATMENT OF HEMATOLOGICAL MALIGNANCIES WITH INHIBITORS OF MENIN | KURA ONCOLOGY, INC. (US) | 2022-04-28 | — | — | WO | disclosed |