Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19618968 | 0.87 | MRGPRX4 (0.47) | MAPTKMT2AMEN1GAALMNA | |
| SCHEMBL19635143 | 0.87 | MAPK13 (0.43) | MAPTKMT2AMEN1GAALMNA | |
| SCHEMBL19615237 | 0.86 | KMT2A (0.46) | MAPTKMT2AMEN1GAALMNA | |
| Hydrochloric Acid SCHEMBL19615637 | 0.86 | MCL1 (0.42) | MAPTKMT2AMEN1GAALMNA | |
| SCHEMBL19635767 | 0.84 | SMN1; SMN2 (0.45) | MAPTKMT2AMEN1GAALMNA | |
| SCHEMBL19615199 | 0.84 | MCL1 (0.41) | MAPTKMT2AMEN1GAALMNA | |
| SCHEMBL19635391 | 0.80 | MAPT (0.34) | MAPTKMT2AMEN1GAALMNA | |
| SCHEMBL19635285 | 0.79 | MAPT (0.43) | MAPTKMT2AMEN1GAAKDM4E | |
| SCHEMBL28643152 | 0.77 | NR1H2 (0.38) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL19635290 | 0.77 | ALDH1A1 (0.41) | MAPTKMT2AMEN1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458459-B1 | MACROCYCLIC INDOLE DERIVATIVES | BAYER AG (DE) | 2022-04-27 | — | — | EP | disclosed |