Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GNPAT | O15228 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31005433 | 0.89 | HDAC1 (0.45) | HDAC1HDAC2SMN1; SMN2ALDH1A1EHMT2 | |
| SCHEMBL24360385 | 0.88 | ALDH1A1 (0.45) | HDAC1HDAC2SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL20998952 | 0.88 | ALDH1A1 (0.45) | HDAC1HDAC2SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL19188184 | 0.87 | HDAC1 (0.47) | HDAC1HDAC2SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL10086909 | 0.81 | ALDH1A1 (0.47) | HDAC1HDAC2SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL898975 | 0.80 | HDAC2 (0.47) | HDAC1HDAC2SMN1; SMN2ALDH1A1 | |
| SCHEMBL25413645 | 0.79 | ALDH1A1 (0.47) | HDAC1HDAC2ALDH1A1EHMT2EHMT1 | |
| SCHEMBL25413647 | 0.79 | ALDH1A1 (0.47) | HDAC1HDAC2ALDH1A1EHMT2EHMT1 | |
| SCHEMBL9915159 | 0.79 | HDAC1 (0.42) | HDAC1HDAC2SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4349165 | 0.78 | ALDH1A1 (0.43) | HDAC1HDAC2SMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022084738-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | Azura Ophthalmics Ltd. (IL) | 2022-04-28 | — | — | WO | disclosed |