SCHEMBL24360385

SCHEMBL24360385

CC(=O)N[C@@H](CSSc1ccccn1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
SMN1; SMN2 Q16637 3/20 0.44
HDAC1 Q13547 2/20 0.41
HDAC2 Q92769 2/20 0.41
HPGD P15428 2/20 0.41
HSD17B10 Q99714 2/20 0.41
PAM P19021 1/20 0.41
EHMT2 Q96KQ7 1/20 0.41
EHMT1 Q9H9B1 1/20 0.41
APOBEC3G Q9HC16 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
PKM P14618 1/20 0.41
LMNA P02545 1/20 0.40
MTNR1A P48039 3/20 0.40
MTNR1B P49286 3/20 0.40
KDM4E B2RXH2 1/20 0.39
NPC1 O15118 1/20 0.39
ALOX15 P16050 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20998952 1.00 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2HDAC1HDAC2HPGD
SCHEMBL24378432 0.88 HDAC1 (0.48) ALDH1A1SMN1; SMN2HDAC1HDAC2HPGD
SCHEMBL9915159 0.87 HDAC1 (0.42) ALDH1A1SMN1; SMN2HDAC1HDAC2HPGD
SCHEMBL20885060 0.86 EHMT2 (0.43) ALDH1A1SMN1; SMN2HDAC1HDAC2HPGD
SCHEMBL30616153 0.85 LMNA (0.48) ALDH1A1SMN1; SMN2HDAC1HDAC2MEN1
SCHEMBL24378375 0.85 LMNA (0.48) ALDH1A1SMN1; SMN2HDAC1HDAC2MEN1
SCHEMBL29092878 0.85 LMNA (0.48) ALDH1A1SMN1; SMN2HDAC1HDAC2MEN1
SCHEMBL14984799 0.83 PPARA (0.55) HDAC1HDAC2
SCHEMBL25800370 0.83 HDAC1 (0.42) ALDH1A1SMN1; SMN2HDAC1HDAC2EHMT2
SCHEMBL13225865 0.82 HDAC1 (0.48) SMN1; SMN2HDAC1HDAC2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119638607-A Sulfide prodrug based on butylphthalide as carrier 中国药科大学 2025-03-18 CN disclosed
US-20230399317-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS Azura Ophthalmics Ltd. (IL) 2023-12-14 US disclosed
US-20230399317-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS Azura Ophthalmics Ltd. (IL) 2023-12-14 US disclosed
CN-116940570-A Compounds and methods for treating ocular disorders 阿祖拉眼科有限公司 2023-10-24 CN disclosed
EP-4232149-A2 COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS AZURA OPHTHALMICS LTD (IL) 2023-08-30 EP disclosed
EP-4232034-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS AZURA OPHTHALMICS LTD (IL) 2023-08-30 EP disclosed
CN-116635032-A Compounds and methods for treating ocular disorders 阿祖拉眼科有限公司 2023-08-22 CN disclosed
US-20220332749-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS Azura Ophthalmics Ltd. (IL) 2022-10-20 US disclosed
WO-2022084738-A2 COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS Azura Ophthalmics Ltd. (IL) 2022-04-28 WO disclosed
WO-2022084739-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS Azura Ophthalmics Ltd. (IL) 2022-04-28 WO disclosed
WO-2022084739-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS Azura Ophthalmics Ltd. (IL) 2022-04-28 WO disclosed
WO-2022084738-A2 COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS Azura Ophthalmics Ltd. (IL) 2022-04-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230399317-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS MPO, MUC1, CRYAB ALDH1A1 489/4885SMN1; SMN2 4754/4885HDAC1 1658/4885
US-20220332749-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS MPO, MUC1, CRYAB ALDH1A1 489/4885SMN1; SMN2 4754/4885HDAC1 1658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.