SCHEMBL24378591

SCHEMBL24378591

CC(C)(C)C(=O)OC(C)(C)C(=O)OCO

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.42
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
ELANE P08246 1/20 0.31
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
ABCB11 O95342 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30
HTR2A P28223 1/20 0.30
PMP22 Q01453 1/20 0.30
PPARA Q07869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL63687 0.83
SCHEMBL23292898 0.82 CYP4F2 (0.44) CYP4F2CYP4A11GAAABCB11CYP1A2
SCHEMBL23292904 0.78 HCAR2 (0.35) PRKCACYP4F2CYP4A11ELANEPOLB
SCHEMBL23293015 0.77 PRKCA (0.43) PRKCATSHR
SCHEMBL26945317 0.75 TSHR (0.41) PRKCACYP3A4TSHR
SCHEMBL23292981 0.75 ALDH1A1 (0.47) CYP4F2CYP4A11CYP1A2TSHR
SCHEMBL23292978 0.73 DGAT1 (0.46) ELANE
SCHEMBL2568905 0.72 PRKCA (0.40) PRKCACYP4F2CYP4A11
SCHEMBL15429216 0.72 PRKCA (0.40) PRKCACYP4F2CYP4A11
SCHEMBL23293010 0.70 TSHR (0.38) PRKCAELANECYP1A2CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3816149-B1 ISOBUTYRIC ESTER COMPOUND HAVING AN ISOBUTYRYLOXY GROUP OR PIVALOYLOXY GROUP AT ALPHA POSITION, AND PERFUME COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2022-04-27 EP disclosed