SCHEMBL24379743

SCHEMBL24379743

CCCCOCCOCCOCCOCCNCCCNC(=O)[C@@H](N)CCCCN

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ GNAI3 P08754 1/20 0.64
▸ GNAO1 P09471 1/20 0.64
▸ GNAI1 P63096 1/20 0.64
▸ TLR2 O60603 6/20 0.54
▸ DPP7 Q9UHL4 3/20 0.53
▸ RRM1 P23921 1/20 0.52
▸ DPP8 Q6V1X1 1/20 0.44
▸ DPP9 Q86TI2 1/20 0.44
▸ SIRT6 Q8N6T7 1/20 0.43
▸ SIRT1 Q96EB6 1/20 0.43
▸ CA2 P00918 1/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ TP53 P04637 1/20 0.41
▸ CYP1A2 P05177 1/20 0.41
▸ CYP2D6 P10635 1/20 0.41
▸ MAPT P10636 1/20 0.41
▸ CYP2C9 P11712 1/20 0.41
▸ CYP2C19 P33261 1/20 0.41
▸ KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28990465 0.87 GNAI3 (0.57) GNAI3GNAO1GNAI1TLR2DPP7
SCHEMBL14616486 0.86 GNAI3 (0.68) GNAI3GNAO1GNAI1TLR2DPP7
SCHEMBL17345951 0.86 GNAI3 (0.81) GNAI3GNAO1GNAI1TLR2DPP7
SCHEMBL14205322 0.84 GNAI3 (0.65) GNAI3GNAO1GNAI1TLR2DPP7
SCHEMBL30094858 0.84 GNAI3 (0.65) GNAI3GNAO1GNAI1TLR2DPP7
SCHEMBL20980376 0.84 GNAI3 (0.63) GNAI3GNAO1GNAI1TLR2DPP7
SCHEMBL20980426 0.84 GNAI3 (0.63) GNAI3GNAO1GNAI1TLR2DPP7
SCHEMBL24379775 0.84 GNAI3 (0.63) GNAI3GNAO1GNAI1TLR2DPP7
SCHEMBL14616487 0.83 GNAI3 (0.63) GNAI3GNAO1GNAI1TLR2DPP7
SCHEMBL12085597 0.83 GNAI3 (0.76) GNAI3GNAO1GNAI1TLR2DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11364200-B2 — — 2022-06-21 — — US disclosed
US-11318099-B2 — — 2022-05-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11364200-B2 — FUS, NSF, MATR3 GNAI3 1843/4885GNAO1 2782/4885GNAI1 2044/4885
US-11318099-B2 — FUS, NSF, MATR3 GNAI3 1843/4885GNAO1 2782/4885GNAI1 2044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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