Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.31 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4442991 | 0.83 | CYP2C9 (0.33) | SMN1; SMN2TP53CYP2C9CYP2C19HIF1A | |
| SCHEMBL16446376 | 0.83 | CYP3A4 (0.40) | — | |
| SCHEMBL13911912 | 0.78 | ALDH1A1 (0.41) | SMN1; SMN2TP53CYP2C9CYP2C19HIF1A | |
| SCHEMBL12733032 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2TP53CYP2C9CYP2C19HIF1A | |
| SCHEMBL10540315 | 0.76 | AHR (0.38) | — | |
| SCHEMBL31497679 | 0.75 | SMN1; SMN2 (0.45) | SMN1; SMN2TP53CYP2C9CYP2C19HIF1A | |
| SCHEMBL16618538 | 0.70 | ALDH1A1 (0.35) | ALDH1A1MAPT | |
| SCHEMBL10279383 | 0.70 | CD44 (0.42) | SMN1; SMN2TP53CYP2C9CYP2C19HIF1A | |
| SCHEMBL10907968 | 0.68 | ALDH1A1 (0.56) | SMN1; SMN2TP53CYP2C9CYP2C19HIF1A | |
| SCHEMBL13990527 | 0.68 | ALDH1A1 (0.34) | SMN1; SMN2TP53CYP2C9CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2654426-A2 | USE OF ISOTHIAZOLECARBOXAMIDES TO CREATE LATENT HOST DEFENSES IN A PLANT | Bayer Intellectual Property GmbH (DE) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012084858-A2 | USE OF ISOTHIAZOLECARBOXAMIDES TO CREATE LATENT HOST DEFENSES IN A PLANT | BAYER CROPSCIENCE AG (DE) | 2012-06-28 | — | — | WO | disclosed |
| WO-2011107443-A1 | USE OF PROPINEB FOR PHYSIOLOGICAL CURATIVE TREATMENT UNDER ZINC DEFICIENCY | BAYER CROPSCIENCE AG (DE) | 2011-09-09 | — | — | WO | disclosed |