SCHEMBL2438871

SCHEMBL2438871

Nc1c(O)cccc1C(F)(F)F

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
G6PD P11413 1/20 0.42
CASP7 P55210 1/20 0.42
CASP6 P55212 1/20 0.42
HSD17B1 P14061 3/20 0.40
HSD17B2 P37059 3/20 0.40
AR P10275 1/20 0.39
TSHR P16473 4/20 0.38
ALDH1A1 P00352 3/20 0.38
TDP1 Q9NUW8 3/20 0.38
POLB P06746 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALOX15 P16050 2/20 0.37
CA2 P00918 3/20 0.36
ADAMTS4 O75173 1/20 0.36
EGFR P00533 1/20 0.36
CA1 P00915 1/20 0.36
LMNA P02545 1/20 0.36
FYN P06241 1/20 0.36
MMP2 P08253 1/20 0.36
MMP9 P14780 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6754030 0.86 G6PD (0.42) G6PDCASP7CASP6HSD17B1HSD17B2
SCHEMBL396026 0.83 POLB (0.44) TSHRALDH1A1TDP1POLBL3MBTL1
SCHEMBL2585650 0.83 G6PD (0.39) G6PDCASP7CASP6HSD17B1HSD17B2
SCHEMBL689225 0.79 G6PD (0.37) G6PDCASP7CASP6TSHRALDH1A1
SCHEMBL144361 0.77 ALDH1A1 (0.60) G6PDCASP7CASP6TSHRALDH1A1
SCHEMBL564620 0.77 ALDH1A1 (0.48) G6PDCASP7CASP6TSHRALDH1A1
SCHEMBL16738112 0.77 G6PD (0.35) G6PDCASP7CASP6TSHRALDH1A1
SCHEMBL28217056 0.77 G6PD (0.35) G6PDCASP7CASP6TSHRALDH1A1
SCHEMBL28938358 0.77 AR (0.40) G6PDCASP7CASP6HSD17B1HSD17B2
SCHEMBL16414055 0.76 MPL (0.44) TSHRALDH1A1TDP1POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117247515-A Polyimide containing Trringer's Base element and gas separation membrane and method prepared by polyimide 西北工业大学 2023-12-19 CN claimed
CN-116854679-A Novel epoxy resin containing imide unit and preparation method thereof 西北工业大学 2023-10-10 CN claimed
CN-116854913-A Preparation method of high-impact-resistance bismaleimide resin 西北工业大学 2023-10-10 CN claimed
CN-111303426-B Polyimide film and method for preparing polyimide film by click chemistry 西北工业大学 2022-07-05 CN claimed
CN-110229158-B Thermosetting polyimide precursor with low melt viscosity and suitable for RTM (resin transfer molding) and preparation method thereof 西北工业大学 2022-06-07 CN claimed
CN-110218287-B High-performance self-repairing polyimide based on dynamic imine bond and preparation method thereof 西北工业大学 2022-03-15 CN claimed
CN-109824894-B Preparation method of polyimide film with molecular main chain alternately composed of two acid anhydrides 西北工业大学 2021-08-10 CN claimed
CN-111303426-A Polyimide film and method for preparing polyimide film by click chemistry 西北工业大学 2020-06-19 CN claimed
CN-110229158-A Low melt viscosity is suitable for the molding Thermocurable polyimide presoma of RTM and preparation method 西北工业大学 2019-09-13 CN claimed
CN-110218287-A A kind of high-performance selfreparing polyimides and preparation method based on dynamic imine linkage 西北工业大学 2019-09-10 CN claimed
CN-109824894-A A kind of Kapton preparation method that molecular backbone is alternately made of two kinds of acid anhydrides 西北工业大学 2019-05-31 CN claimed
CN-119775261-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2025-04-08 CN disclosed
CN-115427404-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-12-13 CN disclosed
CN-117247515-A Polyimide containing Trringer's Base element and gas separation membrane and method prepared by polyimide 西北工业大学 2023-12-19 CN disclosed
CN-116854679-A Novel epoxy resin containing imide unit and preparation method thereof 西北工业大学 2023-10-10 CN disclosed
EP-0298803-A1 Process for the perhaloalkylation of aromatic derivatives RHONE-POULENC CHIMIE (FR) 1989-01-11 EP disclosed
US-4731450-A Process for perfluoroalkylation of aromatic derivatives RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1988-03-15 US disclosed
EP-0206951-A2 Process for the perfluoroalkylation of aromatic derivatives RHONE-POULENC CHIMIE (FR) 1986-12-30 EP disclosed
US-4263441-A BENZOXAZOLE DERIVATIVES HOECHST AKTIENGESELLSCHAFT (DE) 1981-04-21 US disclosed
EP-0002030-A1 Fluorinated benzazole derivatives, method for their preparation and their use as optical brighteners HOECHST AKTIENGESELLSCHAFT (DE) 1979-05-30 EP disclosed