SCHEMBL564620

SCHEMBL564620

CC(C)(c1cccc(O)c1N)c1cccc(O)c1N

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
TDP1 Q9NUW8 4/20 0.48
TSHR P16473 2/20 0.48
CA2 P00918 3/20 0.44
G6PD P11413 1/20 0.42
CASP7 P55210 1/20 0.42
CASP6 P55212 1/20 0.42
TRPA1 O75762 2/20 0.39
ATM Q13315 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
ALOX15 P16050 3/20 0.37
RECQL P46063 3/20 0.36
EGFR P00533 2/20 0.36
LMNA P02545 2/20 0.36
FYN P06241 2/20 0.36
MMP9 P14780 2/20 0.36
HPGD P15428 2/20 0.36
HSD17B10 Q99714 2/20 0.36
ADAMTS4 O75173 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL144361 0.86 ALDH1A1 (0.60) ALDH1A1TDP1TSHRCA2G6PD
SCHEMBL564062 0.86 ESR1 (0.47) ALDH1A1TDP1TSHRCA2G6PD
SCHEMBL1639984 0.79 TDP1 (0.42) ALDH1A1TDP1TSHRCA2G6PD
SCHEMBL8511558 0.79 ALDH1A1 (0.39) ALDH1A1TDP1TSHRCA2G6PD
SCHEMBL30438488 0.78 ESR1 (0.47) ALDH1A1TDP1TSHRCA2G6PD
SCHEMBL2438871 0.77 G6PD (0.42) ALDH1A1TDP1TSHRCA2G6PD
SCHEMBL6754030 0.77 G6PD (0.42) ALDH1A1TDP1TSHRCA2G6PD
SCHEMBL8512559 0.76 CD44 (0.48) ALDH1A1TDP1TSHRCA2CASP7
SCHEMBL986029 0.76 CA2 (0.54) ALDH1A1TDP1TSHRCA2TRPA1
SCHEMBL584830 0.75 ALDH1A1 (0.71) ALDH1A1TDP1TSHRCA2TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311800-A The manufacturing method and aforementioned Ppolynuclear aromatic aminophenol compound, resin combination and solidfied material of Ppolynuclear aromatic aminophenol compound and resin combination DIC株式会社 2019-02-05 CN disclosed
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 EP disclosed
US-20040152862-A1 Optical resins and applications thereof HITACHI CHEMICAL CO., LTD. (JP) 2004-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 ALDH1A1 204/4885TDP1 1337/4885TSHR 2375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.