Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.50 |
| ▸ | DRD3 | P35462 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18829750 | 0.98 | GAA (0.50) | DRD2DRD3L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL30839792 | 0.83 | ADRB1 (0.69) | DRD2DRD3TSHRADRB1HTR1A | |
| SCHEMBL8689 | 0.83 | ADRB1 (0.69) | DRD2DRD3TSHRADRB1HTR1A | |
| Hydrochloric Acid SCHEMBL5373698 | 0.82 | ADRB1 (0.67) | DRD2DRD3ALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL30183272 | 0.82 | ADRB1 (0.67) | DRD2DRD3ALDH1A1KDM4EMAPT | |
| SCHEMBL22521489 | 0.80 | DRD2 (0.56) | DRD2DRD3ALDH1A1GAAMAPT | |
| SCHEMBL23843550 | 0.79 | ADRB1 (0.69) | L3MBTL1ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL8452211 | 0.79 | DRD2 (0.69) | DRD2DRD3L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL329301 | 0.79 | ADRB1 (0.67) | L3MBTL1ALDH1A1GAAMAPTPOLB | |
| SCHEMBL9065218 | 0.78 | LMNA (0.68) | L3MBTL1ALDH1A1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022089406-A1 | NITROGEN-CONTAINING FUSED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海青煜医药科技有限公司 | 2022-05-05 | — | — | WO | disclosed |