Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768492 | 0.97 | TSHR (0.42) | TSHRCYP2D6CYP2C19HIF1AALDH1A1 | |
| Acetic Acid SCHEMBL1695867 | 0.97 | TSHR (0.42) | TSHRCYP2D6CYP2C19HIF1AALDH1A1 | |
| SCHEMBL83915 | 0.79 | TSHR (0.60) | TSHRCYP2D6CYP2C19HIF1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL4137653 | 0.79 | TSHR (0.60) | TSHRCYP2D6CYP2C19HIF1AALDH1A1 | |
| SCHEMBL9015652 | 0.79 | ALDH1A1 (0.37) | TSHRCYP2D6CYP2C19HIF1AALDH1A1 | |
| SCHEMBL25269996 | 0.79 | TSHR (0.46) | TSHRCYP2D6CYP2C19HIF1AALDH1A1 | |
| SCHEMBL15074875 | 0.78 | TET2 (0.43) | TSHRCYP2D6CYP2C19HIF1AALDH1A1 | |
| SCHEMBL17520809 | 0.78 | ALDH1A1 (0.33) | TSHRCYP2D6CYP2C19HIF1AALDH1A1 | |
| SCHEMBL8844260 | 0.77 | TSHR (0.57) | TSHRCYP2D6CYP2C19HIF1AALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL10868076 | 0.77 | TSHR (0.57) | TSHRCYP2D6CYP2C19HIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214409-B | The synthesis of tsiklomitsin and analogue thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-10-21 | — | — | CN | claimed |
| CN-101027279-B | Synthesis of tetracyclines and analogues thereof | HARVARD COLLEGE | 2013-03-27 | — | — | CN | claimed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-110520117-A | Substituted eutectic of glycine compound and application thereof | SYNEURX INT TAIWAN CORP | 2019-11-29 | — | — | CN | disclosed |
| CN-110225914-A | Bicyclic urea kinase inhibitor and application thereof | 布罗德研究所股份有限公司 | 2019-09-10 | — | — | CN | disclosed |
| CN-109666637-A | The application of 2 T of V γ 9V δ and its agonist in treatment liver fibrosis, cirrhosis and liver cancer | 清华大学 | 2019-04-23 | — | — | CN | disclosed |
| CN-109651429-A | The small molecule agonist of 2 T cell of V γ 9V δ of efficient stable | 清华大学 | 2019-04-19 | — | — | CN | disclosed |
| CN-109563018-A | Eutectic of sodium benzoate and application thereof | 心悦生医股份有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109563024-A | Eutectic of lithium benzoate and use thereof | 心悦生医股份有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-105814112-B | Surfactant based on aliphatic polycarbonate | 萨索尔化学品(美国)有限责任公司 | 2019-03-08 | — | — | CN | disclosed |
| CN-109071456-A | MAX binding agents as MYC modulators and uses thereof | 麻省理工学院 | 2018-12-21 | — | — | CN | disclosed |
| EP-0761640-A1 | Process for the preparation of esters of 2-(4-hydroxyphenoxy)-propionic acid | BASF AKTIENGESELLSCHAFT (DE) | 1997-03-12 | — | — | EP | disclosed |
| CN-1128987-A | Novel intermediates for the preparation of antihistaminic piperidine derivatives | MERRELL DOW PHARMA (US) | 1996-08-14 | — | — | CN | disclosed |
| US-5225421-A | Leukotriene antagonists; cytoprotective agents | MERCK FROSST CANADA, INC. (CA) | 1993-07-06 | — | — | US | disclosed |
| EP-0275667-B1 | 3-HETERO-SUBSTITUTED-N-BENZYL-INDOLES | MERCK FROSST CANADA INC. (CA) | 1992-03-18 | — | — | EP | disclosed |
| US-5081138-A | Antiasthmatic, antiallergic, antiinflammatory and cytoprotective agents | MERCK FROSST CANADA, INC. (CA) | 1992-01-14 | — | — | US | disclosed |
| EP-0275667-A1 | 3-hetero-substituted-N-benzyl-indoles | MERCK FROSST CANADA INC. (CA) | 1988-07-27 | — | — | EP | disclosed |
| US-4656170-A | CARDIOTONIC, HYPOTENSIVE, ANTITHROMBOTIC | WARNER-LAMBERT COMPANY (US) | 1987-04-07 | — | — | US | disclosed |
| US-4418142-A | ALDEHYDE SCAVANGERS | AGFA GEVAERT AKTIENGESELLSCHAFT (DE) | 1983-11-29 | — | — | US | disclosed |
| US-3935278-A | MOLYBDENUM OR VANADIUM CONTAINING CATALYST | ATLANTIC RICHFIELD COMPANY (US) | 1976-01-27 | — | — | US | disclosed |