SCHEMBL9768492

SCHEMBL9768492

CC(=O)CC(C)(C)C(=O)O.[Au]

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C19 P33261 1/20 0.42
HIF1A Q16665 1/20 0.42
ALDH1A1 P00352 4/20 0.38
HMGCR P04035 1/20 0.38
CHRM1 P11229 1/20 0.38
TBXA2R P21731 1/20 0.38
ADRA1A P35348 1/20 0.38
ACLY P53396 1/20 0.37
ACACB O00763 1/20 0.35
ACACA Q13085 1/20 0.35
TET2 Q6N021 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
LMNA P02545 1/20 0.33
SLC15A2 Q16348 1/20 0.33
KDM4E B2RXH2 1/20 0.32
FFAR1 O14842 1/20 0.32
CPT2 P23786 1/20 0.32
TRPA1 O75762 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL243901 0.97 TSHR (0.43) TSHRCYP2D6CYP2C19HIF1AALDH1A1
Acetic Acid SCHEMBL1695867 0.94 TSHR (0.42) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL25269996 0.77 TSHR (0.46) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL83915 0.77 TSHR (0.60) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL9015652 0.77 ALDH1A1 (0.37) TSHRCYP2D6CYP2C19HIF1AALDH1A1
Hydrochloric Acid SCHEMBL4137653 0.77 TSHR (0.60) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL15074875 0.76 TET2 (0.43) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL17520809 0.75 ALDH1A1 (0.33) TSHRCYP2D6CYP2C19HIF1AALDH1A1
Ammonia Solution, Strong SCHEMBL10868076 0.74 TSHR (0.57) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL14879687 0.74 TSHR (0.43) TSHRCYP2D6CYP2C19HIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4990363-A Decomposing organometallic compound using glow discharges SCHERING AKTIENGESELLSCHAFT (DE) 1991-02-05 US disclosed