SCHEMBL24390187

SCHEMBL24390187

CCOC(=O)/C(C#N)=C/C=C1\Sc2ccccc2N1C

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 8/20 0.60
▸ FNTB P49356 8/20 0.60
▸ MEN1 O00255 10/20 0.54
▸ KMT2A Q03164 10/20 0.54
▸ MAPT P10636 9/20 0.54
▸ ALDH1A1 P00352 4/20 0.54
▸ MAPK1 P28482 1/20 0.54
▸ L3MBTL1 Q9Y468 1/20 0.54
▸ USP2 O75604 6/20 0.53
▸ CRHBP P24387 2/20 0.53
▸ CRHR2 Q13324 2/20 0.53
▸ HPGD P15428 2/20 0.53
▸ RAB9A P51151 5/20 0.53
▸ SMN1; SMN2 Q16637 4/20 0.53
▸ LMNA P02545 4/20 0.53
▸ GAA P10253 4/20 0.52
▸ NPC1 O15118 3/20 0.52
▸ NPSR1 Q6W5P4 3/20 0.52
▸ HSD17B10 Q99714 1/20 0.47
▸ POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24390191 0.89 FNTA (0.49) FNTAFNTBMEN1KMT2AMAPT
SCHEMBL24390185 0.88 MAPT (0.70) FNTAFNTBMEN1KMT2AMAPT
SCHEMBL24390232 0.82 MAPT (0.78) FNTAFNTBMEN1KMT2AMAPT
SCHEMBL24390195 0.81 MAPT (0.47) FNTAFNTBMEN1KMT2AMAPT
SCHEMBL24390231 0.79 MAPT (0.61) FNTAFNTBMEN1KMT2AMAPT
SCHEMBL10036074 0.78 MAPT (0.61) FNTAFNTBMEN1KMT2AMAPT
SCHEMBL24390184 0.78 MAPT (0.51) FNTAFNTBMEN1KMT2AMAPT
SCHEMBL24390194 0.77 MAPT (0.56) FNTAFNTBMEN1KMT2AMAPT
SCHEMBL13889560 0.77 MAPT (0.52) FNTAFNTBMEN1KMT2AMAPT
SCHEMBL24390183 0.76 MAPT (0.70) FNTAFNTBMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220137260-A1 POLYMERIZABLE COMPOSITION, COMPOUND, POLYMER, RESIN COMPOSITION, ULTRAVIOLET CUT FILM, AND LAMINATE FUJIFILM CORPORATION (JP) 2022-05-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220137260-A1 POLYMERIZABLE COMPOSITION, COMPOUND, POLYMER, RESIN COMPOSITION, ULTRAVIOLET CUT FILM, AND LAMINATE RER1, C5, RAD51 FNTA 3099/4885FNTB 3571/4885MEN1 1611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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